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Small study reveals hidden hurdles to exercise for severe depression

NCT ID NCT05539495

Knowledge-focused Sponsor: University of Nottingham Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study interviewed 12 people with persistent major depression who were referred to a group exercise program. Researchers wanted to understand what makes it easier or harder for them to take part. The goal is to help clinics create exercise programs that better fit the needs of people with severe depression.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this research could help doctors design exercise programs that more people with severe depression are willing and able to join.
What could go wrong
This was a very small study (12 people) at one clinic, so the findings may not apply to everyone with depression. It only looked at reasons for joining, not whether exercise actually helps depression.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

12 people

The number who actually took part.

Started

Dec 2022

Finished

Apr 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients with persistent major depression who have at least agreed to referral to the Exercise Recovery Group at the Nottingham Specialist Depression Service within the previous 24 months

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with persistent major depression * Patients who have at least agreed to referral to the Exercise Recovery Group within the previous 24 months * Patients who are able to provide informed consent. Exclusion Criteria: * Patients with a main diagnosis of Bipolar Disorder. * Patients who cannot speak fluently in English. * Patients without an email account or access to an electronic device that could be used for the MS Teams meeting. * Patients who are younger than 18-years-old. There is no upper age limit.

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Conditions

The condition(s) this trial relates to.

major depressive disorder Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Depression moderate Depression severe Major depressive disorder

Contacts and locations

Locations

  • Nottinghamshire Healthcare NHS Foundation Trust

    Nottingham, Nottinghamshire, NG3 6AA, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.