Can exercise and diet beat muscle loss in seniors? new study says maybe
NCT ID NCT07028294
First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tested a 12-week program combining exercise (stretching, resistance, and aerobic) with personalized nutrition (including high-protein drinks) in 80 older adults aged 65-90 who have sarcopenia (muscle loss) and metabolic syndrome. The goal was to see if the program improves muscle strength, physical performance, and quality of life. Results were measured at 12 and 24 weeks after the program started.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- combined exercise and nutrition intervention
- What this could lead to
- If successful, this program could provide a practical, non-drug approach to improve muscle strength and physical function in older adults with sarcopenia and metabolic syndrome.
- What could go wrong
- This is a small, completed empirical study without a control group, so results may not be generalizable. The intervention requires adherence to exercise and diet, which may be challenging for some participants.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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80 people
The number who actually took part.
- Started
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Sep 2023
- Finished
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Jul 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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65 to 90 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * patients older than 65 years and under 90 years * patients who meet the criteria for the Asian Working Group for Sarcopenia (AWGS) 2019 * patients who had metabolic syndrome Exclusion Criteria: * patients with less than estimated glomerular filtration rate (eGFR) 30 * patients with musculoskeletal or chronic lung disease incapable of exercise * patients with untreated or uncontrolled cardiovascular disease which may affect muscle mass or performing exercise * patients less than 5 years after treatment of malignant tumor * patients with liver cirrhosis, diabetes and other chronic disease * patients who cannot perform combined exercise nutrition intervention for other reasons
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Seoul National University Bundang Hospital
Seongnam-si, Gyeonggi-do, 13620, South Korea
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