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Gentle exercise and massage may ease hemophilia joint pain, small study suggests

NCT ID NCT06535971

Symptom relief Sponsor: Far Eastern Memorial Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a personalized program of exercise and manual therapy (like stretching and massage) in 10 adults with severe hemophilia who had multiple damaged joints. The goal was to see if it could reduce pain, improve joint movement and strength, boost heart-lung fitness, and enhance quality of life. Participants received tailored sessions based on their current condition, and the study measured outcomes like joint health, pain scores, walking ability, and daily function.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
manual therapy and exercise
What this could lead to
If it works, this could offer a non-drug way to manage pain and improve mobility for people with severe hemophilia and joint damage.
What could go wrong
This is a very small, completed study with only 10 participants, so results may not apply to everyone. The therapy is personalized and not standardized.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

10 people

The number who actually took part.

Started

Jul 2024

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * over 20 years old and diagnosed with severe hemophilia * those who receive prophylaxis regularly * there are more than 2 target joints (hemophilic arthropathy) Exclusion Criteria: * unwilling to sign the informed consent * any neurological disease or specific musculoskeletal condition (such as fracture) one year ago * more than 3 (excluding 3) joint replacement surgeries (different joints) * unable to walk due to hemophilia joint disease or any other diseases * major bleeding events that pose risks or hinder research * unable to follow instructions due to cognitive impairment

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Conditions

The condition(s) this trial relates to.

hemophilia A hemophilic arthropathy Motor Activity severe hemophilia A

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Severe hemophilia

Contacts and locations

Locations

  • Far Eastern Memorial hospital

    New Taipei City, 220, Taiwan

More trials for these conditions

Other studies related to the condition(s) this trial covers.