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Exercise program aims to boost strength and quality of life in advanced breast cancer

NCT ID NCT07521826

Symptom relief Sponsor: State University of Londrina Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a supervised exercise program combining resistance training and walking can improve physical function, fitness, and quality of life in women with stage IV breast cancer. 78 women currently on medical treatment will be randomly assigned to either the exercise group or a control group. The program includes warm-up, strength exercises, and aerobic walking, with progress tailored to each participant's ability.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
combined exercise training program (resistance and aerobic exercises)
What this could lead to
If it works, this could show that structured exercise helps women with metastatic breast cancer maintain physical function and improve quality of life.
What could go wrong
This is a small, early-stage trial (78 participants) testing a non-drug intervention, so results may not apply broadly. Exercise may be difficult for some participants due to disease or treatment side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 78 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Apr 2026

An estimate. Start dates often move.

Expected to finish

Dec 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Women aged ≥ 18 years; * Confirmed diagnosis of stage IV (metastatic) breast cancer; * Currently undergoing medical treatment; * Willingness and functional independence to participate in the exercise program; * Medical clearance to engage in structured physical exercise. Exclusion Criteria: * Presence of unstable bone metastases. * Untreated or symptomatic brain metastases; * Evidence of severe cardiovascular disease identified by electrocardiogram (ECG); * Severe active infection; * Uncontrolled severe respiratory insufficiency or dependence on supplemental oxygen at rest or during exercise; * Uncontrolled severe pain; * Any other medical condition contraindicating participation in physical exercise; * Conditions that impair adherence to study procedures or the ability to provide informed consent; * Pregnancy.

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Conditions

The condition(s) this trial relates to.

breast carcinoma cancer metastatic neoplasm muscular atrophy neoplasm Neoplasm Metastasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cancer Metastases

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Universidade Estadual de Londrina, Londrina

    Londrina, Paraná, 86047-597, Brazil

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