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Sweating out anxiety: study tests High-Intensity exercise as treatment

NCT ID NCT04638946

Symptom relief Sponsor: NYU Langone Health Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether different intensities of exercise can reduce anxiety in adults with anxiety disorders. 110 sedentary adults with high anxiety sensitivity were assigned to either low-intensity exercise or a program that gradually increased to high-intensity exercise over 8 weeks. Researchers measured changes in anxiety sensitivity and overall anxiety severity using standard questionnaires.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
exercise (low intensity or titration to high intensity)
What this could lead to
If it works, this could point toward a simple, drug-free way to ease anxiety symptoms using exercise.
What could go wrong
This is a small, early-stage study with no blinding, so results may not be reliable or apply to everyone. Exercise may not work for all types of anxiety.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

110 people

The number who actually took part.

Started

Jun 2021

Finished

Apr 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria * Males and females ages 18-65 * Primary psychiatric diagnosis of generalized anxiety disorder (GAD), social anxiety disorder, or panic disorder * Anxiety Sensitivity Index-3 score of ≥23 (i.e., high anxiety sensitivity) * Currently sedentary (≤60 minutes of moderate intensity exercise per week for the past 3 months) * Body mass index \<40 * Able and willing to provide informed consent Exclusion Criteria * Lifetime history of Bipolar I or II or any psychotic disorder * Bulimia or anorexia in the past 6 months * Substance use disorder in the past 3 months * Current PTSD (past PTSD is allowed) * High current suicide risk (active suicidal ideation with plan and intent) as indicated by a score of ≥4 on the Columbia Suicide Severity Rating Scale (C-SSRS) consistent with a need for referral to higher level of care

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Conditions

The condition(s) this trial relates to.

anxiety anxiety disorder generalized anxiety disorder panic disorder social phobia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anxiety

Contacts and locations

Locations

  • NYU Langone Health

    New York, New York, 10016, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.