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Parkinson's breakthrough? exercise and brain zaps show promise

NCT ID NCT07524400

Symptom relief Sponsor: Universidad Rey Juan Carlos Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether combining physical exercise with a gentle, non-invasive brain stimulation technique (tDCS) can improve walking, balance, and reaction time in people with Parkinson's disease. Researchers will measure changes in movement speed and coordination in 100 participants. The goal is to find a safe, drug-free way to ease movement symptoms.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

May 2026

An estimate. Start dates often move.

Expected to finish

Aug 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Clinical diagnosis of idiopathic Parkinson's disease, established according to the UK Parkinson's Disease Society Brain Bank Criteria. Ability to understand and comply with study procedures. Stable antiparkinsonian medication regimen prior to study participation. Exclusion Criteria: Significant cognitive impairment, defined as a score \< 23 on the Mini-Mental State Examination (MMSE). Below-average premorbid intelligence, defined as a score \< 40 on the Vocabulary subtest of the Wechsler Adult Intelligence Scale - Third Edition (WAIS-III). Clinically significant depression, defined as a score \> 10 on the Geriatric Depression Scale (GDS-15). Current treatment with cholinesterase inhibitors. Presence of severe cardiovascular disease, including but not limited to: Congestive heart failure Ischemic heart disease Cardiac pacemaker Orthostatic hypotension Uncontrolled diabetes mellitus. History of stroke or traumatic brain injury. History of seizure disorder or epilepsy. Presence or prior implantation of a deep brain stimulation (DBS) device. History of major orthopedic surgery that could interfere with motor performance or gait. Presence of implanted electronic devices, including cardiac pacemakers, incompatible with study procedures.

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Parkinson disease

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Center of Sport Research

    RECRUITING

    Fuenlabrada, Madrid, 28992, Spain

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