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Can exercise ease statin muscle pain? new study investigates

NCT ID NCT07563452

Knowledge-focused Sponsor: Raffaele Mazzolari Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study looks at how different types and intensities of exercise affect muscle recovery in people taking statins compared to those not on statins. Researchers will test cycling and resistance training at various levels, measuring muscle damage markers and pain sensitivity. The goal is to find safer, more personalized exercise recommendations for statin users.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Dose-escalation exercise protocol (cycling and resistance training)
What this could lead to
If successful, this study could help tailor exercise advice for people on statins to reduce muscle pain and damage.
What could go wrong
This is a small pilot study with only 40 participants, so results may not apply to everyone. It measures short-term muscle markers, not long-term outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2026

Expected to finish

Jun 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

30 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Sedentary behavior (defined as \< 1 hour of planned physical activity per week) * Low occupational physical activity * Age between 30 and 65 years * Non-smoker * Medical clearance to partake in physical exercise (as determined during screening visit) * For statin users: Current statin medication with stable dosage for at least 8 weeks prior to enrollment * For controls: Statin-naïve individuals Exclusion Criteria: * BMI \< 20 kg/m² or \> 30 kg/m² * Smoking or smoking cessation \< 1 year ago * Medical conditions or musculoskeletal issues that preclude eligibility for full physical effort or interfere with outcome measures * Medication (other than statins) that may interfere with physical exercise or outcome measures (assessment on a case-by-case basis during screening visit) * Any condition identified during screening (e.g., abnormal ECG, cardiopulmonary exercise test) that, in the opinion of the physician, precludes safe participation

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Conditions

The condition(s) this trial relates to.

short stature-auditory canal atresia-mandibular hypoplasia-skeletal anomalies syndrome statin toxicity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Statin adverse reaction

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University of Innsbruck

    RECRUITING

    Innsbruck, Tyrol, 6020, Austria

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