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Frozen shoulder breakthrough? losartan plus exercise tested in new trial

NCT ID NCT07513350

Symptom relief Sponsor: Istanbul University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether adding the blood pressure medication losartan to a standard exercise program can improve pain, movement, and function in people with frozen shoulder. About 33 adults with frozen shoulder will be randomly assigned to receive either exercise alone or exercise plus losartan for four weeks. Researchers will measure shoulder function, pain levels, and range of motion at the start, after four weeks, and again at eight weeks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 33 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2026

Expected to finish

Jan 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 years or older diagnosed with frozen shoulder (adhesive capsulitis) * Having less than 50% of range of motion (ROM) in at least one of the following shoulder movements compared to the unaffected side: external rotation, abduction, flexion, or internal rotation * Having more than 25% loss of ROM in at least two movement planes compared to the unaffected shoulder * Patients in stage II or III of frozen shoulder Exclusion Criteria: * Women who are pregnant, breastfeeding, or planning pregnancy during the study * Patients in stage I of frozen shoulder * Patients diagnosed with inflammatory or other types of arthritis due to autoimmune diseases affecting the shoulder * Patients with rotator cuff pathology and/or glenohumeral arthritis * Patients with a history of prior shoulder infection * Patients with hypotension * Patients who have undergone previous upper extremity surgery or plan to undergo upper extremity surgery during the study period * Patients with allergy to losartan or its active/inactive components * Patients taking medications known to have adverse interactions with losartan * Patients who, in the investigator's opinion, have any medical condition, laboratory abnormality, or history that could pose risk, contraindicate participation, affect the conduct, objectives, or evaluation of the study, or prevent full participation in the study

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Conditions

The condition(s) this trial relates to.

bursitis frozen shoulder Shoulder Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Adhesive capsulitis of shoulder

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Istanbul University-Cerrahpasa

    RECRUITING

    Istanbul, Turkey (Türkiye)

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