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Veterans sharpen thinking skills from home in new TBI study

NCT ID NCT04111549

Symptom relief Sponsor: VA Office of Research and Development Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jul 02, 2026 · Updated 2 times

Summary

This study tested a home-based program to help aging veterans with a history of traumatic brain injury (TBI) improve their thinking skills, such as attention and planning. Twenty-nine veterans aged 65 and older used telehealth technology to complete cognitive exercises from home. The goal was to see if this approach could boost daily functioning and make treatment more accessible for older veterans.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

29 people

The number who actually took part.

Started

Sep 2020

Finished

Sep 2025

Lead sponsor

A government agency

The lead sponsor is a US federal agency other than the NIH.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

65 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Veterans aged 65 or older with history of chronic TBI (\>6 months post-injury) -- sustained either during military service * including in combat * or as a civilian * Self-reported cognitive complaints \[1 moderate or severe cognitive symptom(s) on the Neurobehavioral Symptom Inventory (NSI \[58\]) that interfere(s) with daily function\] * Endorsement of comfort and familiarity with technology and/or the possession of a personal computer, or other HBT-compatible device * i.e., tablet, or smartphone * Per the investigators' preliminary patient survey, approximately 75% of the target population has access to a personal computer * Participants who do not endorse comfort/familiarity with technology may be eligible to participate if they can identify a family member or other caregiver who is consistently present and willing to assist with connecting to study sessions * A limited number of VA-issued tablets will be available for use by participants who do not have access to a personal computer or other HBT-compatible device Exclusion Criteria: Moderate-severe objective cognitive impairment, as measured by score \<20 on the Montreal Cognitive Assessment (MoCA \[59-61\]), that interferes with daily functioning (i.e., Major Neurocognitive Disorder) * Unstable medical, neurologic, or psychiatric conditions precluding participation in research activities * Other reasons for being unable or unwilling to participate in study procedures * Ongoing illicit or prescription drug (Mini International Neuropsychiatric Interview Version 7.0.2 (MINI) \[79\] or alcohol abuse (Alcohol Use Disorders Test-Consumption (AUDIT-C) \[62\]\>8) * Active psychosis * Poor English comprehension

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Conditions

The condition(s) this trial relates to.

Brain Injuries, Traumatic traumatic brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Brain injuries, traumatic Executive dysfunction

Contacts and locations

Locations

  • San Francisco VA Medical Center, San Francisco, CA

    San Francisco, California, 94121-1563, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.