Virtual reality could help spot thinking problems in MS patients

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: PATIENTS * Male or female * Age 18-60 years * RRMS diagnosis according to McDonald criteria (Polman et al., 2005); * Treated with Aubagio® (Indication for first line therapy) * Native French speaking * Being affiliated to health insurance * Having signed an informed consent (at the latest on the day of inclusion and before any examination required by research) HEALTHY CONTROLS * Male or Female, * Age 18-60 years * Willing to participate and to sign informed consent. * Being affiliated to health insurance * Having signed an informed consent (at the latest on the day of inclusion and before any examination required by research) Exclusion Criteria: PATIENTS * History of neurological disease and/or other neurological diseases, * Psychiatric comorbidity including severe depression according to DSM-IV, * Alcohol or other addiction to toxic, * Disabling visual or motor problems preventing participation to neuropsychological assessments, * Acquisition disorders : Dyslexia, Dysphasia, Dyscalculia and dyspraxia, * Dosage change, stop or start of hypnotic or anxiolytic or antidepressive treatment less than 30 days * Relapse since less than one month, * Steroid treatment less than one month (be taken orally or by infusion) at the dosage of 500mg daily, * Prior neuropsychological testing with the same tests less than 6 months * Contra-indication to MRI (pacemakers, aneurysm clips, artificial heart valves, ear implants, metal fragments or foreign objects in the eyes, skin or body, claustrophobia) or refusing MRI * Illiteracy, is unable to count or to read * Pregnant or breastfeeding women * Patient concerned by articles L 1121-5 to L 1121-8 (persons deprived of their liberty by a judicial or administrative decision, minors, persons of legal age who are the object of a legal protection measure or unable to express their consent) HEALTHY CONTROLS * History of neurological disease and/or neurological diseases * Psychiatric comorbidity including severe depression according to DSM-IV; * Alcohol or other toxic addiction; * Known cognitive complaint or neuropsychological affection * Hypnotic or anxiolytic or antidepressive treatment, * Prior neuropsychological testing with the same tests less than 6 months * Acquisition disorders: Dyslexia, Dysphasia, Dyscalculia and dyspraxia, * Steroid treatment less than one month (be taken orally or by infusion) at the dosage of 500mg daily, * Contra-indication to MRI (pacemakers, aneurysm clips, artificial heart valves, ear implants, metal fragments or foreign objects in the eyes, skin or body, claustrophobia) or refusing MRI * Illiteracy, is unable to count or to read * Pregnant or breastfeeding women * Person concerned by articles L 1121-5 to L 1121-8 (persons deprived of their liberty by a judicial or administrative decision, minors, persons of legal age who are the object of a legal protection measure or unable to express their consent)