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New hope for rare vascular tumors: everolimus trial launches

NCT ID NCT07477548

First seen Mar 20, 2026 · Last updated Jun 19, 2026 · Updated 16 times

Summary

This phase 2 trial tests the drug everolimus in 67 people with vascular malformations or tumors that haven't responded to other treatments. The goal is to see if the drug can shrink these growths and improve symptoms. Participants take everolimus daily for 6 months, with doses adjusted based on age and other medications.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Everolimus (a targeted cancer drug that blocks a protein called mTOR to slow abnormal blood vessel growth)

What this could lead to

If successful, this could offer a new treatment option for people with rare, treatment-resistant vascular malformations and tumors.

What could go wrong

This is an early-phase, single-center trial with no control group, so results may not apply broadly. Everolimus can cause side effects like mouth sores, infections, and metabolic changes.

Conditions

The condition(s) this trial relates to.

arteriovenous hemangioma/malformation arteriovenous malformations of the brain familial multiple nevi flammei hemangioendothelioma hemangioma Kasabach-Merritt syndrome lymphangioma melanocytic nevus tufted angioma vascular malformation vascular neoplasm venous hemangioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.