Needle-Free blood vessel connection for dialysis patients tested

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult (age \>18 years old) * Currently on chronic dialysis or expected to be started on chronic dialysis within 3 months of planned endoAVF creation * Target treatment vein diameter(s) for fistula creation ≥ 2.0 mm as measured via Duplex Ultrasound or Venogram * Target treatment artery diameter(s) for fistula creation ≥ 2.0 mm as measured via Duplex Ultrasound or Arteriogram * Both radial and ulnar artery flow to the hand, as confirmed with Duplex Ultrasound and/or Allen's test (i.e.: palmar arch) Exclusion Criteria: * Known central venous stenosis or central vein narrowing \> 50% based on imaging on the same side as the planned AVF creation * Absence of perforator feeding the target cannulation vein(s) via Venogram * Occlusion or stenosis \>50% of target cannulation cephalic or basilic vein * Significantly compromised (≥50% stenosis) flow in the treatment arm * Documented ejection fraction (EF) ≤35% in the last 6 months * Pregnant women * New York Heart Association (NYHA) class III or IV heart failure * Hypercoagulable state * Known bleeding diathesis * Documented history of drug abuse including intravenous drugs within six months of AVF creation * "Planned" concomitant major surgical procedure within 6 months of enrollment or previous major surgery within 30 days of enrollment * Known allergy to contrast dye which cannot be adequately pre-medicated * Known adverse effects to sedation and/or anesthesia which cannot be adequately pre-medicated * Evidence of active infections on the day of the index procedure * Estimated life expectancy \< 1 year * Patient is not willing to provide written informed consent, is not geographically stable and/or not willing to comply with required follow-up * Patient with a target cannulation vein that is \> 6mm deep that would require a transposition procedure, defined as the elevation of a target cannulation vein AND the creation of a new AV fistula * Patient is not willing to undergo a 2nd stage procedure as defined in Section 4.5.3 of the study protocol.