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Hidden artery could be key to better sex life after prostate surgery

NCT ID NCT07597798

Symptom relief Sponsor: University College, London Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether saving a small extra artery to the penis during robotic prostate cancer surgery can help men recover erections. About 1 in 3 men have this artery, and the study will use MRI scans to find it before surgery. Researchers will follow 20-40 men for a year to see if preserving the artery improves sexual function and quality of life.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2026

Expected to finish

Jan 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients with localised prostate cancer undergoing radical prostatectomy with bilateral nerve sparing.

Ages

18 to 79 years

Sex

Male participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Men diagnosed with cT2-T3a N0 M0 PCa aged between 18 and 79 from all ethnic backgrounds. * Patients who underwent a prostate mpMRI before prostate biopsy. * Medically fit to undergo RARP. * Diagnostic quality prostate biopsies concordant with a diagnostic quality prostate mpMRI adequate to provide a surgical plan. * Scheduled for RARP with a recommendation of NVB spare based on multidisciplinary meetings informed by mpMRI, biopsy result and clinical factors. * Sexually active men with no to mild ED at baseline based on IIEF-EFD (\>=24) questionnaire. * Preference to preserve erectile function for sexual intercourse. * Ability to read English sufficiently to understand PIS and able to give informed consent. Exclusion Criteria: * Established moderate/ severe ED (IIEF-EFD \<24) * Patients who received neo-adjuvant androgen deprivation therapy. * Patients with previous surgery for benign prostatic enlargement * Patients who received previous treatment for prostate cancer: External beam radiotherapy, brachytherapy, focal therapy, chemotherapy. * Previous pelvic or penile fracture * Previous surgery for ED * Poor quality prostate mpMRI or biparametric MRI (no contrast) * Established vascular disease (ischaemic heart disease, cerebrovascular disease, peripheral vascular disease)

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Conditions

The condition(s) this trial relates to.

erectile dysfunction prostate cancer vasculogenic impotence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Erectile dysfunction due to arterial insufficiency Erectile dysfunction following radical prostatectomy Radical prostatectomy Robotic radical prostatectomy

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University College London Hospitals NHS foundation trust

    RECRUITING

    London, W1G 8PH, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.