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New drug cocktail aims to wipe out bladder cancer before surgery

NCT ID NCT05239624

First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 28 times

Summary

This study tests whether giving two drugs—enfortumab vedotin and pembrolizumab—before bladder cancer surgery can eliminate cancer in the lymph nodes and shrink tumors. About 23 adults with advanced bladder cancer that has spread to lymph nodes will receive the combination before their cystectomy. The goal is to see if this approach leads to a complete response, meaning no cancer remains in the removed tissue.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-••••

Locations

  • Baptist Alliance MCI

    ACTIVE_NOT_RECRUITING

    Miami, Florida, 33143, United States

  • Lehigh Valley Health Network (Data Collection Only)

    RECRUITING

    Allentown, Pennsylvania, 18103, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering -Nassau

    RECRUITING

    Commack, New York, 11725, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Basking Ridge

    RECRUITING

    Basking Ridge, New Jersey, 07920, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Bergen

    RECRUITING

    Montvale, New Jersey, 07645, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Cancer Center

    RECRUITING

    New York, New York, 10065, United States

    Contact Phone: •••-•••-••••

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Monmouth

    RECRUITING

    Middletown, New Jersey, 07748, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Nassau

    RECRUITING

    Rockville Centre, New York, 11553, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Westchester

    RECRUITING

    Harrison, New York, 10604, United States

    Contact Phone: •••-•••-••••

  • University of Texas Southwestern Medical Center at Dallas

    ACTIVE_NOT_RECRUITING

    Dallas, Texas, 75390, United States

Conditions

Explore the condition pages connected to this study.