Can collagen shots or shockwaves fix heel pain?
NCT ID NCT06138236
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-phase trial tests whether shockwave therapy, collagen peptide injections, or a combination of both can reduce pain and improve foot function in people with plantar fasciitis. Eighty-four adults with heel pain are randomly assigned to one of three groups. Researchers will measure pain during walking and overall foot function over time.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Collagen hydrolyzed peptides (Arthrys) and/or extracorporeal shock wave therapy (ESWT)
- What this could lead to
- If it works, this could point toward a simpler, non-surgical option to ease heel pain and improve walking.
- What could go wrong
- This is a very early, small trial (84 people) with no placebo group, so results may not be conclusive or apply to everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Early phase 1
The earliest testing in people: a first look at safety, in a very small group.
- Participants
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About 84 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2023
- Expected to finish
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Dec 2025
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Plantar fascitiis Aged between 18 and 80 years old Exclusion Criteria: * Previous surgery of the foot * Contraindications to ESWT
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Angela Notarnicola
RECRUITINGBari, 70124, Italy
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Other studies related to the condition(s) this trial covers.
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