New nerve block may offer better pain control after C-Section
NCT ID NCT07582640
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two types of nerve blocks—erector spinae plane (ESP) block and transversus abdominis plane (TAP) block—for pain relief after cesarean section. Sixty women will receive one of the two blocks after surgery, and their pain levels and need for morphine will be tracked for 24 hours. The goal is to see if the ESP block provides better pain control, especially for deeper internal pain, than the standard TAP block.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- nerve block (erector spinae plane block or transversus abdominis plane block)
- What this could lead to
- If ESP block works better, it could offer women a more effective pain relief option after C-section, reducing the need for strong painkillers like morphine.
- What could go wrong
- This is a small, early-stage study with only 60 participants. The results may not apply to all women, and the ESP block might not prove superior to the standard TAP block.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Apr 2026
An estimate. Start dates often move.
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 40 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age from 18 to 40 years old. * Pregnant women. * Scheduled for lower-segment cesarean section. * American Society of Anesthesiologists (ASA) physical status I-II. * Singleton pregnancy at ≥37 weeks' gestation. Exclusion Criteria: * • Contraindications to regional blocks or local anesthetics. * History of chronic analgesic use or opioid dependency. * Coagulopathy or anticoagulant therapy. * Local infection at the injection site. * Allergy to study medications. * Patient refusal.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Sohag Faculty of Medicine
Sohag, Egypt