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Which nerve block eases rib fracture pain better?

NCT ID NCT07756047

Symptom relief Sponsor: Sunnybrook Health Sciences Centre Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 10, 2026 · Last updated Aug 11, 2026 · Updated 1 time

Summary

This trial compares two types of continuous nerve block catheters—erector spinae plane (ESP) and serratus anterior plane (SAP)—for managing pain in people with traumatic rib fractures. The goal is to see which provides better pain relief, reduces opioid use, and improves breathing. Adults with at least three rib fractures and significant pain are eligible. Participants are randomly assigned to receive one of the two catheter infusions, and their pain, opioid consumption, and respiratory function are measured over 72 hours.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Erector spinae plane (ESP) catheter infusion or serratus anterior plane (SAP) catheter infusion
What this could lead to
If one technique proves better, it could become the standard for managing rib fracture pain, reducing opioid reliance and improving recovery.
What could go wrong
This is a small, single-center trial, and results may not apply broadly. Both techniques carry risks like infection or block failure, and the better option may not be clear.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 66 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Jun 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age \>18; * Traumatic rib fractures (unilateral or bilateral); * Minimum of 3 rib fractures per side; * Admitted to hospital for \<72 hours * NRS pain score \> 4 at rest or with movement for chest pain at the time of eligibility assessment Exclusion Criteria: * Severe traumatic brain injury (Glasgow Coma Scale \< 9); * Surgery performed/planned within 72 hours of catheter infusion start; * Uncontrolled coagulopathy; * Skin infection or anatomical abnormality (i.e. open fracture) at insertion sites; * Allergy to local anesthetic; * Chronic high dose opioid use preadmission (Morphine Equivalent Dose \> 30mg per day); * Pregnancy; * Acute respiratory failure requiring intubation at enrolment; * Inability to comply with Intravenous Patient-Controlled Analgesia use; * Contraindications to nerve blocks * High likelihood of loss to follow-up

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Conditions

The condition(s) this trial relates to.

Acute Pain injury Rib Fractures

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Traumatic rib fracture Traumatic rib fracture(S)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Sunnybrook Health Sciences Centre

    Toronto, Ontario, M4N 3M5, Canada