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Nerve block may ease broken rib pain in emergency care

NCT ID NCT07494851

Symptom relief Sponsor: Nottingham University Hospitals NHS Trust Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a nerve block called an erector spinae plane (ESP) block is practical to use in trauma patients with broken ribs. It included 27 adults with rib fractures and moderate to severe pain. The goal was to see if a larger trial is possible, not to prove the block works.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
ESP block (nerve block procedure)
What this could lead to
If successful, this could lead to a larger trial testing whether ESP blocks provide better pain relief for rib fractures than standard care alone.
What could go wrong
This is a very small feasibility study (27 participants) focused on recruitment and retention, not on proving pain relief. The results may not apply to all trauma patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

27 people

The number who actually took part.

Started

Jul 2022

Finished

Feb 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Age ≥ 18 Mechanism of injury blunt thoracic trauma Radiographic evidence of 1 or more new traumatic rib fractures Moderate or severe unilateral acute pain (defined as 11-point numerical rating scale (NRS) pain \>4 when patient performing vital capacity breath or effective cough) at time of enrolment. Patients may have bilateral fractures, but pain must be unilateral. Exclusion Criteria: Patient refusal or inability to give informed written consent for any reason Thoracic injury requiring emergent operative or interventional radiology management Allergy to local anaesthetic Infection at site of ESP block Actual or estimated

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Conditions

The condition(s) this trial relates to.

bone fracture Rib Fractures

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Rib fractures

Contacts and locations

Locations

  • Barts Health NHS Trust

    London, United Kingdom

  • Manchester University NHS Foundation Trust

    Manchester, United Kingdom

  • Queens Medical Centre

    Nottingham, United Kingdom

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