Sleep aid showdown: which anesthetic helps you rest after egg retrieval?
NCT ID NCT06284668
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether esketamine or remimazolam, two drugs used during egg retrieval, could help reduce sleep problems and anxiety the night after the procedure. 315 women aged 18-45 took part. The main goal was to see which drug led to better sleep quality on the first night after surgery.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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315 people
The number who actually took part.
- Started
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Mar 2024
- Finished
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May 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 45 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Age 18-45 years old; 2. American society of Aneshesiologists(ASA)physical status classification system is grade I-III; 3. Elective surgery is proposed 4. BMI of 19-30 kg/m2; 5. Patients who agreed to enroll in this study voluntarily Exclusion Criteria: 1. Those who are known to be allergic to the drug ingredients in this study and their allergic constitution; 2. Allergic history of general anesthesia drugs, opioid drugs, non-steroidal drugs; 3. History of neurological diseases; History of chronic pain; Drug and alcohol addiction; A long history of opioid use; Opiates were given 48 hours before surgery 4. Coronary heart disease, bronchial asthma, severe hypertension, severe blood system dysfunction, liver and kidney function, electrolyte abnormalities; 5. Respiratory insufficiency, respiratory failure; 6. BMI\<18 kg/m2 or BMI\>30kg/m2; 7. Poor compliance, unable to complete the experiment according to the study plan; Participants who have participated in clinical trials of other drugs within the last 4 weeks; 8. Preoperative Pittsburgh Sleep Quality Index (PSQI) higher than 7 9. Any circumstances deemed unsuitable for inclusion by the researcher for any reason.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Tianjin Medical University General Hospital
Tianjin, 300052, China
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