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New study tests Scope-Based cancer removal as surgery alternative

NCT ID NCT03039309

Disease control Sponsor: Portsmouth Hospitals NHS Trust Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 29, 2026 · Last updated Sep 18, 2026 · Updated 3 times

Summary

This study looks at how well a procedure called endoscopic submucosal dissection (ESD) works for removing early-stage cancers in the digestive tract. ESD uses a special knife on a thin tube to cut out abnormal tissue in one piece, avoiding open surgery. Researchers are tracking 500 adults in the UK to see how often the cancer is completely removed and how safe the procedure is over two years.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Endoscopic submucosal dissection (a procedure using an endoscopic knife to remove lesions in the gastrointestinal tract)
What this could lead to
If successful, this could confirm endoscopic submucosal dissection as a reliable, less invasive alternative to surgery for early gastrointestinal cancers.
What could go wrong
This is an observational study, not a randomized trial, so results may not prove superiority over other treatments. Complications such as bleeding or perforation are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 500 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2016

Expected to finish

Aug 2028

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients undergoing endoscopic submucosal dissection for early gastrointestinal neoplasia (e.g colorectal/gastric/oesophageal) in tertiary referral centres in the UK

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male or Female, aged 18 years or above undergoing endoscopic submucosal dissection * Participant is able to give informed consent for participation in the study Exclusion Criteria: * Patients under the age of 18 * Patients unable to give informed consent

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Endoscopic submucosal dissection

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Portsmputh Hospitals NHS Trust

    RECRUITING

    Portsmouth, PO6 3LY, United Kingdom

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