Could a simple injection prevent a common ERCP complication?
NCT ID NCT07173179
First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 31 times
Summary
This study tested whether injecting epinephrine around the bile duct opening, combined with a standard rectal anti-inflammatory drug (indomethacin), could prevent pancreatitis after ERCP—a common and serious complication. Over 500 patients were randomly assigned to receive either the combo or indomethacin alone. The goal was to see if the extra injection lowers pancreatitis rates further.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Duzce University School of Medicine
Düzce, 81620, Turkey (Türkiye)
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
epinephrine injection and rectal indomethacin
What this could lead to
If it works, this could offer a simple, low-cost way to lower the risk of pancreatitis after ERCP, making the procedure safer for patients.
What could go wrong
This is a completed Phase 4 trial, but the benefit may be small or not apply to all patients. Epinephrine injection carries risks like bleeding or tissue damage.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.