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Spinal stimulation may restore function after Conus-Region injury

NCT ID NCT07717606

Disease control Sponsor: Istanbul Gelisim University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 21, 2026 · Last updated Jul 22, 2026 · Updated 1 time

Summary

This study tests whether epidural electrical stimulation, combined with a structured rehabilitation program, can improve functional independence in people with spinal cord injury affecting the conus region. Participants receive an implanted stimulator and undergo task-oriented exercises, balance training, and mobility practice over six months. The goal is to see if this combination can enhance self-care, breathing, bladder/bowel control, and movement.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Epidural electrical stimulation delivered through an implanted device, combined with structured rehabilitation
What this could lead to
If successful, this approach could improve mobility, self-care, and bladder/bowel function in people with spinal cord injury involving the conus region.
What could go wrong
This is a small, early exploratory study with only 29 participants, so results may not apply broadly. The procedure involves surgical implantation and carries risks such as infection or device complications.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

29 people

The number who actually took part.

Started

Jan 2026

Finished

Jan 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consisted of individuals with chronic spinal cord injury involving the conus region (T12 and/or L1) who received epidural electrical stimulation integrated with a structured rehabilitation program. Twenty-nine participants (20 males and 9 females; age range 17-61 years) with complete baseline and follow-up assessments were included in the final analysis.

Ages

17 to 61 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults and adolescents aged 17 to 61 years. * Diagnosis of chronic spinal cord injury involving the conus region (T12 and/or L1). * Underwent epidural electrical stimulation (EES) combined with a structured rehabilitation program. * Available baseline and follow-up Spinal Cord Independence Measure (SCIM) assessments. * Provided written informed consent or consent was obtained from a legally authorized representative. Exclusion Criteria: * Spinal cord injury without conus-region involvement. * Missing baseline or follow-up functional assessment data. Incomplete clinical records preventing outcome evaluation. * Contraindications to epidural electrical stimulation or inability to participate in the rehabilitation program.

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Conditions

The condition(s) this trial relates to.

spinal cord injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Conus medullaris injury Conus region involvement Spinal cord injury

Contacts and locations

Locations

  • Istanbul Gelisim University

    Istanbul, Istanbul, 34310, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.