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New drug combo shows promise for hard-to-treat lymphoma

NCT ID NCT05852717

First seen Jan 12, 2026 · Last updated May 01, 2026 · Updated 19 times

Summary

This study tests a new combination of the drug epcoritamab plus chemotherapy (GDP) in 32 adults with relapsed or refractory large B-cell lymphoma. The goal is to see if this combo can shrink tumors enough to allow patients to proceed to a stem cell transplant or CAR T-cell therapy. Participants receive 3 cycles of the combo, then may continue epcoritamab alone if they respond but cannot have transplant.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Indiana University Melvin and Bren Simon Comprehensive Cancer Center

    RECRUITING

    Indianapolis, Indiana, 46202, United States

    Contact Email: •••••@•••••

    Contact

  • Karmanos Cancer Center (Wayne State University)

    RECRUITING

    Detroit, Michigan, 48201, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Texas Southwestern Medical Center

    RECRUITING

    Dallas, Texas, 75390, United States

    Contact

    Contact Email: •••••@•••••

  • University of Virginia Health System

    RECRUITING

    Charlottesville, Virginia, 22908, United States

    Contact

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.