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New drug epcoritamab tested in Real-World lymphoma patients

NCT ID NCT06830759

Disease control Sponsor: AbbVie Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows about 700 adults with advanced diffuse large B-cell lymphoma or follicular lymphoma who are receiving epcoritamab as part of their routine care. Researchers will track how well the drug controls the cancer over up to 3 years. The goal is to see if results from clinical trials hold up in real-world settings.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
epcoritamab
What this could lead to
If successful, this study could confirm that epcoritamab works well in everyday clinical practice for people with advanced lymphoma who have tried other treatments.
What could go wrong
This is an observational study, not a controlled trial, so results may be less definitive. Epcoritamab is still investigational and may cause side effects like cytokine release syndrome.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 700 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2025

Expected to finish

Sep 2031

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult participants who are being treated with epcoritamab for Diffuse Large B-Cell and Follicular Lymphoma

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participants who are scheduled to be treated with epcoritamab for Treatment after two or more prior lines of therapy 3L+ diffuse large B-cell lymphoma ((D)LBCL) or 3L+ Follicular lymphoma (FL). * Treatment with epcoritamab should be administered in accordance with the approved local label in the participating country. * The decision to treat the participant should have been made by the clinician prior to, and independently of any decision to approach the participant to participate in this study. Exclusion Criteria: * Any condition included in the contraindications section of the approved local epcoritamab label in the participating country. * Participation in a concurrent interventional clinical trial (not including non-interventional/ observational study, PMOS, or registry participation) from enrollment and throughout the study.

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Conditions

The condition(s) this trial relates to.

diffuse large B-cell lymphoma follicular lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Diffuse large B-cell lymphoma Follicular lymphoma

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    73 sites in 13 countries. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • A.O.U. CITTA' DELLA SALUTE E DELLA SCIENZA DI TORINO - Ospedale Molinette /ID# 275283

    RECRUITING

    Turin, Piedmont, 10126, Italy

  • AHEPA University General Hospital of Thessaloniki /ID# 273633

    RECRUITING

    Thessaloniki, 54636, Greece

  • AZ Oostende /ID# 273714

    RECRUITING

    Ostend, West-Vlaanderen, 8400, Belgium

  • Acibadem City Clinic Tokuda University Hospital EAD /ID# 273659

    RECRUITING

    Sofia, 1407, Bulgaria

  • Agios Andreas Hospital Patras /ID# 273629

    RECRUITING

    Pátrai, Achaia, 26335, Greece

  • Algemeen Ziekenhuis klina /ID# 273405

    RECRUITING

    Brasschaat, Antwerpen, 2930, Belgium

  • Azienda Ospedaliera Universitaria Policlinico Tor Vergata /ID# 274572

    RECRUITING

    Rome, Roma, 00133, Italy

  • Azienda Ospedaliera di Rilievo Nazionale Antonio Cardarelli /ID# 274215

    RECRUITING

    Naples, Napoli, 80131, Italy

  • Cabrini Hospital Malvern /ID# 277780

    RECRUITING

    Malvern, Victoria, 3144, Australia

  • Calvary Mater Newcastle /ID# 277783

    RECRUITING

    Waratah, New South Wales, 2298, Australia

  • Centre Hospitalier Epicura - Hornu /ID# 273406

    RECRUITING

    Boussu, Hainaut, 7301, Belgium

  • Centro de Especialidades Hemato-Oncologicas /ID# 275286

    RECRUITING

    Mexico City, 11520, Mexico

  • Cheltenham General Hospital /ID# 272746

    RECRUITING

    Cheltenham, Gloucestershire, GL53 7AN, United Kingdom

  • Complejo Hospitalario Universitario A Coruña /ID# 272040

    RECRUITING

    A Coruña, A Coruna, 15006, Spain

  • Cross Cancer Institute /ID# 271504

    RECRUITING

    Edmonton, Alberta, T6G 1Z2, Canada

  • Eastern Health - General Hospital /ID# 272062

    RECRUITING

    St. John's, Newfoundland and Labrador, A1B 3V6, Canada

  • Evangelismos Hospital /ID# 272736

    RECRUITING

    Athens, Attica, 10676, Greece

  • Fundacion Argentina contra la Leucemia (FUNDALEU) /ID# 274390

    RECRUITING

    Buenos Aires, 1227, Argentina

  • General Hospital Of Thessaloniki G. Papanikolaou /ID# 275323

    RECRUITING

    Thessaloniki, 57010, Greece

  • General Hospital of Athens Laiko /ID# 272758

    RECRUITING

    Athens, Attica, 11527, Greece

  • General Hospital of Thessaloniki Hippokrateio /ID# 273635

    RECRUITING

    Thessaloniki, 54642, Greece

  • Grand Hôpital De Charleroi - Notre Dame /ID# 273728

    RECRUITING

    Charleroi, Hainaut, 6000, Belgium

  • Groupe Sante CHC - Clinique du MontLegia /ID# 273407

    RECRUITING

    Liège, Liege, 4000, Belgium

  • Hadassah Medical Center-Hebrew University /ID# 271616

    RECRUITING

    Jerusalem, 91120, Israel

  • Health Sciences North /ID# 274738

    RECRUITING

    Greater Sudbury, Ontario, P3E 5J1, Canada

  • Helora /ID# 273726

    RECRUITING

    La Louvière, Hainaut, 7100, Belgium

  • Hematologica Alta Especialidad /ID# 275279

    RECRUITING

    Huixquilucan de Degollado, 52787, Mexico

  • Hospital Britanico de Buenos Aires /ID# 274419

    RECRUITING

    Ciudad Autonoma de Buenos Aire, Buenos Aires, 1280, Argentina

  • Hospital Clinico Universitario de Valladolid /ID# 272042

    RECRUITING

    Valladolid, 47003, Spain

  • Hospital Costa del Sol /ID# 272431

    RECRUITING

    Marbella, Malaga, 29603, Spain

  • Hospital General Universitario Morales Meseguer /ID# 272466

    RECRUITING

    Murcia, 30008, Spain

  • Hospital Italiano de Buenos Aires /ID# 274418

    RECRUITING

    Buenos Aires, 1181, Argentina

  • Hospital Privado Universitario De Córdoba /ID# 274457

    RECRUITING

    Córdoba, Córdoba Province, 5016, Argentina

  • Hospital Universitari Parc Tauli /ID# 272044

    RECRUITING

    Sabadell, Barcelona, 08208, Spain

  • Hospital Universitario Austral /ID# 274393

    RECRUITING

    Pilar, Buenos Aires, 1629, Argentina

  • Hospital Universitario De Burgos /ID# 272066

    RECRUITING

    Burgos, 09006, Spain

  • Hospital Universitario Nuestra Señora de Candelaria /ID# 272413

    RECRUITING

    Santa Cruz de Tenerife, 38010, Spain

  • Hospital Universitario Reina Sofia /ID# 272051

    RECRUITING

    Córdoba, Cordoba, 14004, Spain

  • Hospital Universitario de Navarra /ID# 272041

    RECRUITING

    Pamplona, Navarre, 31008, Spain

  • Hospital Universitario de Valme /ID# 272050

    RECRUITING

    Seville, Sevilla, 41014, Spain

  • Hospital de Manises /ID# 272046

    RECRUITING

    Manises, Valencia, 46940, Spain

  • I.R.C.C.S Istituto Tumori Giovanni Paolo II /ID# 274217

    RECRUITING

    Bari, 70124, Italy

  • IRCCS Ospedale San Raffaele /ID# 274789

    RECRUITING

    Milan, Milano, 20132, Italy

  • Institut Català d'Oncologia (ICO) - Badalona /ID# 272043

    RECRUITING

    Badalona, Barcelona, 08916, Spain

  • Instituto Alexander Fleming /ID# 277284

    RECRUITING

    Ciudad Autonoma de Buenos Aire, Buenos Aires F.D., 1426, Argentina

  • Kingston General Hospital /ID# 272061

    RECRUITING

    Kingston, Ontario, K7L 2V7, Canada

  • Krankenhaus Der Barmherzigen Brueder Graz /ID# 273288

    RECRUITING

    Graz, Styria, 8020, Austria

  • Landeskrankenhaus Hochsteiermark, Standort Leoben /ID# 273266

    RECRUITING

    Leoben, Styria, 8700, Austria

  • Metaxa Cancer Hospital Of Piraeus /ID# 273623

    RECRUITING

    Piraeus, Attica, 18537, Greece

  • Milton Keynes Hospital /ID# 272817

    RECRUITING

    Milton Keynes, Buckinghamshire, MK6 5LD, United Kingdom

  • NHS Lanarkshire /ID# 276471

    RECRUITING

    Airdrie, North Lanarkshire, ML6 0JS, United Kingdom

  • Nepean Cancer Centre, Nepean Hospital /ID# 277782

    RECRUITING

    Kingswood, New South Wales, 2747, Australia

  • Nottingham City Hospital /ID# 272753

    RECRUITING

    Nottingham, Nottinghamshire, NG5 1PB, United Kingdom

  • Ospedale La Maddalena /ID# 274411

    RECRUITING

    Palermo, 90146, Italy

  • Papageorgiou General Hospital /ID# 272735

    RECRUITING

    Thessaloniki, 56429, Greece

  • Queen Alexandra Hospital /ID# 272744

    RECRUITING

    Portsmouth, Hampshire, PO6 3LY, United Kingdom

  • Rabin Medical Center. /ID# 271614

    RECRUITING

    Petah Tikva, 4941492, Israel

  • Royal Cornwall Hospital /ID# 272747

    RECRUITING

    Truro, Cornwall, TR1 3LQ, United Kingdom

  • Specialized Hospital For Active Treatment Of Haematology Diseases /ID# 274955

    RECRUITING

    Sofia, 1756, Bulgaria

  • Tel Aviv Sourasky Medical Center /ID# 271615

    RECRUITING

    Tel Aviv, Tel Aviv, 6423906, Israel

  • The Christie /ID# 272745

    RECRUITING

    Manchester, M20 4BX, United Kingdom

  • The Moncton Hospital /ID# 277230

    RECRUITING

    Moncton, New Brunswick, E1C 6Z8, Canada

  • The Newcastle Upon Tyne Hospitals NHS Foundation Trust /ID# 272748

    RECRUITING

    Newcastle upon Tyne, NE3 3HD, United Kingdom

  • Umhat Sveti Ivan Rilsky /ID# 274898

    RECRUITING

    Sofiya, Sofia, 1606, Bulgaria

  • Unidade Local de Saude de Coimbra, EPE /ID# 272720

    RECRUITING

    Coimbra, 3000-075, Portugal

  • Unidade Local de Saúde Trás-os-Montes e Alto Douro /ID# 275404

    RECRUITING

    Vila Real, 5000-185, Portugal

  • Universitair Ziekenhuis Brussel /ID# 273403

    RECRUITING

    Jette, Brussels Capital, 1090, Belgium

  • University General Hospital Attikon /ID# 272738

    RECRUITING

    Athens, Attica, 12462, Greece

  • University General Hospital of Alexandroupoli /ID# 272737

    RECRUITING

    Alexandroupoli, Evros, 68100, Greece

  • University Hospital of Ioannina /ID# 272739

    RECRUITING

    Ioannina, 45500, Greece

  • University Multiprofile Hospital for Active Treatment Dr. Georgi Stranski /ID# 274893

    RECRUITING

    Pleven, 5800, Bulgaria

  • Vitaz /Id# 273408

    RECRUITING

    Sint-Niklaas, Oost-Vlaanderen, 9100, Belgium

  • Ziekenhuis Oost-Limburg, Campus St.-Jan /ID# 273729

    RECRUITING

    Genk, Limburg, 3600, Belgium

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