New radiotracer aims to spot hidden cancers
NCT ID NCT07400263
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a new radioactive tracer called [68Ga]Ga-PN-EpC1 for PET/CT scans in 30 people with suspected or confirmed epithelial tumors. The tracer targets a protein called EpCAM found on many cancer cells. Researchers want to see if it can find tumors more accurately than standard imaging, and if it's safe. Participants get one injection before their planned biopsy or surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- [68Ga]Ga-PN-EpC1 radiotracer
- What this could lead to
- If successful, this could lead to a more accurate imaging method for detecting epithelial cancers, helping doctors see tumors that other scans might miss.
- What could go wrong
- This is a small, early-phase study with only 30 participants, so results may not apply to everyone. The radiotracer may not work well for all tumor types or could cause side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2026
- Expected to finish
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Dec 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Patients with diagnosed or suspected tumors visiting the hospital between January 2026 and December 2026, who are scheduled for pathological biopsy or surgical treatment within 2 months. 2. Age \> 18 years, regardless of gender. 3. Adequate organ and bone marrow function as defined by the following laboratory values: * Hematology: WBC ≥4.0×10\^9/L or ANC ≥1.5×10\^9/L; PLT ≥100×10\^9/L; Hemoglobin ≥90 g/L. * Liver Function: Total bilirubin ≤1.5× ULN; ALT and AST ≤2.5× ULN (or ≤5× ULN if liver metastases are present). * Renal Function: BUN ≤1.5× ULN; Serum Creatinine (SCr) ≤1.5× ULN. 4. Normal cardiac function. 5. Expected life expectancy ≥12 weeks. 6. Presence of at least one measurable target lesion according to RECIST v1.1 criteria. 7. Patients recommended by clinicians to undergo PET/CT examination for tumor diagnosis and staging. 8. Women of childbearing potential must have a negative pregnancy test within 7 days prior to the examination. Male and female patients of reproductive age must agree to use effective contraception during the study and for at least 3 months after the examination. 9. Voluntarily participate in the study, demonstrate full understanding of the protocol, and provide written informed consent. Exclusion Criteria: 1. Severe laboratory abnormalities, including significant impairment of hepatic or renal function, or severe hematological dysfunction. 2. History of allergic diseases. 3. Patients planning for pregnancy during the study period. 4. Pregnant or lactating women. 5. Inability to maintain a supine position for at least 30 minutes. 6. Patients with claustrophobia or other diagnosed psychiatric disorders that may interfere with compliance. 7. Any other condition that, in the opinion of the investigator, may increase the risk to the subject or interfere with the evaluation of the study results.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Peking University People's Hospital
RECRUITINGBeijing, Beijing Municipality, 100044, China
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