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New radiotracer aims to spot hidden cancers

NCT ID NCT07400263

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new radioactive tracer called [68Ga]Ga-PN-EpC1 for PET/CT scans in 30 people with suspected or confirmed epithelial tumors. The tracer targets a protein called EpCAM found on many cancer cells. Researchers want to see if it can find tumors more accurately than standard imaging, and if it's safe. Participants get one injection before their planned biopsy or surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
[68Ga]Ga-PN-EpC1 radiotracer
What this could lead to
If successful, this could lead to a more accurate imaging method for detecting epithelial cancers, helping doctors see tumors that other scans might miss.
What could go wrong
This is a small, early-phase study with only 30 participants, so results may not apply to everyone. The radiotracer may not work well for all tumor types or could cause side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2026

Expected to finish

Dec 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Patients with diagnosed or suspected tumors visiting the hospital between January 2026 and December 2026, who are scheduled for pathological biopsy or surgical treatment within 2 months. 2. Age \> 18 years, regardless of gender. 3. Adequate organ and bone marrow function as defined by the following laboratory values: * Hematology: WBC ≥4.0×10\^9/L or ANC ≥1.5×10\^9/L; PLT ≥100×10\^9/L; Hemoglobin ≥90 g/L. * Liver Function: Total bilirubin ≤1.5× ULN; ALT and AST ≤2.5× ULN (or ≤5× ULN if liver metastases are present). * Renal Function: BUN ≤1.5× ULN; Serum Creatinine (SCr) ≤1.5× ULN. 4. Normal cardiac function. 5. Expected life expectancy ≥12 weeks. 6. Presence of at least one measurable target lesion according to RECIST v1.1 criteria. 7. Patients recommended by clinicians to undergo PET/CT examination for tumor diagnosis and staging. 8. Women of childbearing potential must have a negative pregnancy test within 7 days prior to the examination. Male and female patients of reproductive age must agree to use effective contraception during the study and for at least 3 months after the examination. 9. Voluntarily participate in the study, demonstrate full understanding of the protocol, and provide written informed consent. Exclusion Criteria: 1. Severe laboratory abnormalities, including significant impairment of hepatic or renal function, or severe hematological dysfunction. 2. History of allergic diseases. 3. Patients planning for pregnancy during the study period. 4. Pregnant or lactating women. 5. Inability to maintain a supine position for at least 30 minutes. 6. Patients with claustrophobia or other diagnosed psychiatric disorders that may interfere with compliance. 7. Any other condition that, in the opinion of the investigator, may increase the risk to the subject or interfere with the evaluation of the study results.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Peking University People's Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100044, China

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