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New combo shows promise for Hard-to-Treat GI cancers

NCT ID NCT05205330

First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 30 times

Summary

This study tests a combination of two drugs—vorbipiprant and balstilimab—in people with advanced colorectal or other gastrointestinal cancers that have stopped responding to standard treatments. The goal is to see if the combination is safe and can shrink or control tumors. About 107 participants will receive the treatment, and researchers will monitor side effects and tumor response.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Azienda Ospedaliero Universitaria Pisana

    Pisa, Pisa, 56126, Italy

  • Istituto Nazionale dei Tumori

    Milan, Milano, 20133, Italy

  • Istituto Oncologico Veneto IRCCS

    Padova, Padova, 35128, Italy

Conditions

Explore the condition pages connected to this study.