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New hope for tough prostate cancer: drug combo targets bone tumors

NCT ID NCT03344211

First seen Nov 17, 2025 · Last updated Jun 17, 2026 · Updated 28 times

Summary

This study looks at men with advanced prostate cancer that no longer responds to hormone therapy and has spread to bones. It compares the drug enzalutamide alone versus enzalutamide plus a radioactive treatment (radium-223) to see how they affect the immune system and bone tumors. The goal is to find better ways to control the disease, not to cure it.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Cedars Sinai Medical Center

    Los Angeles, California, 90048, United States

  • City of Hope

    Duarte, California, 91010, United States

  • USC / Norris Comprehensive Cancer Center

    Los Angeles, California, 90033, United States

Conditions

The condition(s) this trial relates to.

castration-resistant prostate carcinoma metastatic prostate carcinoma prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.