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Targeted drug shows promise for rare genetic cancers

NCT ID NCT05199584

First seen Mar 09, 2026 · Last updated May 18, 2026 · Updated 12 times

Summary

This study tested an experimental drug called ENV-101 (Taladegib) in 20 people with advanced solid tumors that have a specific genetic change (PTCH1 mutation). The goal was to see if the drug could shrink tumors and to check for side effects. Participants had cancers that did not respond to other treatments.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Research Site

    Los Angeles, California, 90095, United States

  • Research Site

    Santa Rosa, California, 95403, United States

  • Research Site

    Tampa, Florida, 33609, United States

  • Research Site

    Zion, Illinois, 60099, United States

  • Research Site

    Covington, Louisiana, 70433, United States

  • Research Site

    Las Vegas, Nevada, 89102, United States

  • Research Site

    New York, New York, 10065, United States

  • Research Site

    Durham, North Carolina, 27710, United States

  • Research Site

    Cincinnati, Ohio, 45229, United States

  • Research Site

    Columbus, Ohio, 43210, United States

  • Research Site

    Pittsburgh, Pennsylvania, 15232, United States

  • Research Site

    Nashville, Tennessee, 37203, United States

  • Research Site

    Houston, Texas, 77030, United States

  • Research Site

    Fredericksburg, Virginia, 22408, United States

  • Research Site

    Lynchburg, Virginia, 24501, United States

  • Research Site

    Madison, Wisconsin, 53792, United States

Conditions

Explore the condition pages connected to this study.