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Can a gene therapy shot ease diabetic foot pain for a year?

NCT ID NCT04873232

First seen Nov 01, 2025 · Last updated May 21, 2026 · Updated 32 times

Summary

This study looked at whether a medicine called Engensis can safely reduce pain from diabetic nerve damage in the feet and legs over 6 extra months. 106 adults who had already been in a related study took part. The goal was to see if the pain relief lasts and if the treatment is safe for long-term use.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Arizona Research Center

    Phoenix, Arizona, 85053, United States

  • California Medical Clinic for Headache

    Los Angeles, California, 90048, United States

  • ClinPoint Trials LLC

    Waxahachie, Texas, 75165, United States

  • Clinical Research Professionals

    Chesterfield, Missouri, 63005, United States

  • Clinical Trials - Little Rock

    Little Rock, Arkansas, 72205, United States

  • Clinical Trials Research - Sacramento

    Sacramento, California, 95821, United States

  • Dominion Medical Associates

    Richmond, Virginia, 23219, United States

  • Eastern Virginia Medical School

    Norfolk, Virginia, 23510, United States

  • Foot & Ankle Center of Illinois

    Springfield, Illinois, 62704, United States

  • Futuro Clinical Trials

    McAllen, Texas, 78501, United States

  • Gateway Clinical Trials, LLC

    O'Fallon, Illinois, 62269, United States

  • Health Concepts

    Rapid City, South Dakota, 57702, United States

  • Innovative Research of West Florida, Inc.

    Clearwater, Florida, 33756, United States

  • Manassas Clinical Research Center

    Manassas, Virginia, 20110, United States

  • Nerve and Muscle Center of Texas

    Houston, Texas, 77030, United States

  • Richmond Behavioral Associates

    Staten Island, New York, 10314, United States

Conditions

Explore the condition pages connected to this study.