Brain training with a twist: music and spanish lessons may stave off memory decline
NCT ID NCT03271190
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a 4-month program that combines memory strategies with fun leisure activities like music or Spanish lessons, plus brain games. It involves 144 adults who feel their memory is getting worse but still test in the normal range. The goal is to see if this approach can improve memory, daily function, and brain health over two years.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- cognitive training combined with leisure activities (music or Spanish lessons) and videogames
- What this could lead to
- If it works, this could point toward a non-drug program to help maintain memory and thinking skills in people who feel their memory is slipping.
- What could go wrong
- This is an early-stage study with no control group for the leisure component, and results may not apply to everyone. The benefits, if any, might be small or not last long-term.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 144 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2017
- Expected to finish
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Jun 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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60 to 85 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Possess sufficient visual and auditory acuity to undergo neuropsychological tests and to do the intervention. * Commit for the whole intervention + 2 follow-up sessions 2 years from pre-test. * Have an internet connection at home. * Answer 'Yes' to both following questions: "Do you feel like your memory is becoming worse?" "Does this worry you?" * Have a delayed recall score above the education-adjusted cut-offs (≥9 for 16+ years of education; ≥5 for 8-15 years of education; ≥3 for 0-7 years of education) at the Logical Memory test (Wechsler Memory Scale, maximum score 25). * Have a Montreal Cognitive Assessment (MoCA) total score of 20 and above (≥20/30). * Have a delayed recall score at the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) Word List task above 4 (\>4). * Have a global Clinical Dementia Rating score (CDR) equal to 0 or 0.5 (=0 to 0.5). Exclusion Criteria: * The presence of disease or injury of the central nervous system, such as: moderate to severe chronic static leukoencephalopathy (including previous traumatic injury), multiple sclerosis, a serious developmental handicap, subdural hematoma (past or current), subarachnoid haemorrhage (past or current), primary cerebral tumour or cerebral metastases, epilepsy (current), dementia or another neurodegenerative disease, and other rarer brain illnesses. * Symptomatic stroke within the previous year. * History of intracranial surgery. * Major surgery within last 2 months. * Serious comorbid condition that, in the opinion of the study investigator, is likely to result in death within a year. * Major depression or anxiety. * Schizophrenia or other major psychiatric disorder. * Ongoing alcohol or drug abuse that in the opinion of the investigator may interfere with the subject's ability to comply with the study procedures. * Subject does not have a study partner who can provide corroborative information. * Individuals where English (Toronto) or French (Montreal) is not sufficiently proficient for clinical assessment and neuropsychological testing. * Unable to undergo MRI scan due to medical contraindications or inability to tolerate the procedure. * Plans on moving outside the province within the next 2 years. * Musicianship: more than 5 years of formal music training in total life or more than 10 years of choir experience. * Fluency in Spanish: has learned Spanish after secondary school for more than 5 years, speaks Spanish at home, has ever lived in a Hispanic country.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CRIUGM
Montreal, Quebec, h3w 1w4, Canada
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Rotman Research Institute, Baycrest
Toronto, Ontario, M6A 2E1, Canada
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