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Brain training with a twist: music and spanish lessons may stave off memory decline

NCT ID NCT03271190

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a 4-month program that combines memory strategies with fun leisure activities like music or Spanish lessons, plus brain games. It involves 144 adults who feel their memory is getting worse but still test in the normal range. The goal is to see if this approach can improve memory, daily function, and brain health over two years.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
cognitive training combined with leisure activities (music or Spanish lessons) and videogames
What this could lead to
If it works, this could point toward a non-drug program to help maintain memory and thinking skills in people who feel their memory is slipping.
What could go wrong
This is an early-stage study with no control group for the leisure component, and results may not apply to everyone. The benefits, if any, might be small or not last long-term.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 144 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2017

Expected to finish

Jun 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

60 to 85 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Possess sufficient visual and auditory acuity to undergo neuropsychological tests and to do the intervention. * Commit for the whole intervention + 2 follow-up sessions 2 years from pre-test. * Have an internet connection at home. * Answer 'Yes' to both following questions: "Do you feel like your memory is becoming worse?" "Does this worry you?" * Have a delayed recall score above the education-adjusted cut-offs (≥9 for 16+ years of education; ≥5 for 8-15 years of education; ≥3 for 0-7 years of education) at the Logical Memory test (Wechsler Memory Scale, maximum score 25). * Have a Montreal Cognitive Assessment (MoCA) total score of 20 and above (≥20/30). * Have a delayed recall score at the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) Word List task above 4 (\>4). * Have a global Clinical Dementia Rating score (CDR) equal to 0 or 0.5 (=0 to 0.5). Exclusion Criteria: * The presence of disease or injury of the central nervous system, such as: moderate to severe chronic static leukoencephalopathy (including previous traumatic injury), multiple sclerosis, a serious developmental handicap, subdural hematoma (past or current), subarachnoid haemorrhage (past or current), primary cerebral tumour or cerebral metastases, epilepsy (current), dementia or another neurodegenerative disease, and other rarer brain illnesses. * Symptomatic stroke within the previous year. * History of intracranial surgery. * Major surgery within last 2 months. * Serious comorbid condition that, in the opinion of the study investigator, is likely to result in death within a year. * Major depression or anxiety. * Schizophrenia or other major psychiatric disorder. * Ongoing alcohol or drug abuse that in the opinion of the investigator may interfere with the subject's ability to comply with the study procedures. * Subject does not have a study partner who can provide corroborative information. * Individuals where English (Toronto) or French (Montreal) is not sufficiently proficient for clinical assessment and neuropsychological testing. * Unable to undergo MRI scan due to medical contraindications or inability to tolerate the procedure. * Plans on moving outside the province within the next 2 years. * Musicianship: more than 5 years of formal music training in total life or more than 10 years of choir experience. * Fluency in Spanish: has learned Spanish after secondary school for more than 5 years, speaks Spanish at home, has ever lived in a Hispanic country.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CRIUGM

    Montreal, Quebec, h3w 1w4, Canada

  • Rotman Research Institute, Baycrest

    Toronto, Ontario, M6A 2E1, Canada

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