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New drug offers hope for babies with rare, deadly artery disease

NCT ID NCT07473973

First seen Mar 16, 2026 · Last updated May 22, 2026 · Updated 7 times

Summary

This study tests a new medicine called INZ-701 in babies up to 1 year old who have a rare genetic condition called ENPP1 deficiency. The condition causes severe hardening of the arteries and rickets. The goal is to see if the medicine can raise a key substance in the blood, improve survival, and protect the heart. About 12 infants will receive the drug for 52 weeks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Azienda Ospedaliera Universitaria Meyer

    RECRUITING

    Florence, 50139, Italy

  • Gyermekgyogyaszat, DE

    RECRUITING

    Debrecen, Hungary

  • Hopital Necker - Enfants Malades

    RECRUITING

    Paris, 75015, France

  • Hospital Sant Joan de Deu Edificio Consultas Externas. Unitat de Recerca

    RECRUITING

    Barcelona, Esplugues de Llobregat, 08950, Spain

  • Hospital Universitario Pedro Ernesto/Rio de Janeiro

    RECRUITING

    Rio de Janeiro, 20551-030, Brazil

  • King Faisal Specialist Hospital and Research Center

    RECRUITING

    Riyadh, 12713, Saudi Arabia

  • Royal Manchester Children's Hospital

    RECRUITING

    Manchester, M13 9WL, United Kingdom

  • Umraniye Traiing and Research Hospital

    RECRUITING

    Istanbul, Turkey (Türkiye)

Conditions

Explore the condition pages connected to this study.