Can a scope solve Kids' mysterious tummy troubles?
NCT ID NCT07154940
First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study will examine 100 children aged 6 to 18 who have had chronic abdominal pain for at least 3 months. Doctors will perform an upper endoscopy (a camera down the throat) to see how often it finds abnormalities in the stomach or intestines. The goal is to understand if this procedure is helpful for diagnosing the cause of persistent belly pain in children.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could show that endoscopy is a useful tool for diagnosing causes of chronic abdominal pain in children, guiding better treatment decisions.
- What could go wrong
- This is an observational study, not testing a treatment. It may find that endoscopy rarely detects abnormalities, limiting its value. Results may not apply to all children.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Oct 2025
An estimate. Start dates often move.
- Expected to finish
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Apr 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Children with chronic abdominal pain
- Ages
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6 to 18 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Children aged 6 to 18 years presenting with chronic abdominal pain which defined according to the Rome IV criteria as persistent or recurring abdominal pain that has been present for at least 3 months, with symptom onset at least 6 months prior to diagnosis. This pain must be continuous or nearly continuous, and only occasionally related to physiological events like eating or defecation. Furthermore, the pain must limit some aspect of daily functioning, and it is not feigned or explained by another medical condition and referred to GIT unit for Esophagogastroduodenoscopy and not undertreatment based on clinical judgment due to the presence of one or more of the following: * Alarm symptoms (e.g., weight loss, anemia, Hematemesis, Dysphagia, persistent vomiting, nocturnal pain) * Failure of empiric therapy (e.g., proton pump inhibitors or dietary modifications) * Suspicion of an underlying organic disease (e.g., celiac disease or Helicobacter pylori infection) Exclusion criteria: 1. Acute abdominal pain 2. Children aged less than 6 years and more than 18 years 3. Recent use of proton pump inhibitors (within 2 weeks) or antibiotics (within 4 weeks) before endoscopy. 4. Children meeting the criteria of functional abdominal pain according to Rome IV criteria in which was defined as as recurrent or chronic abdominal pain that is not explained by another medical condition and is not solely associated with physiological events like eating or menstruation. It must occur at least 4 times per month for at least 2 months, and diagnostic evaluation should rule out other conditions . 5. Children with contraindications to undergoing EGD (e.g., severe respiratory or cardiac conditions). 6. Children who refuse to participate or whose parents do not provide consent. 7. Children previously diagnosed with recurrent abdominal pain -
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.