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New pill combo aims to beat back rare leukemia

NCT ID NCT04324112

First seen Nov 11, 2025 · Last updated Apr 30, 2026 · Updated 24 times

Summary

This study tests whether taking two oral drugs (encorafenib and binimetinib) together works better than the current drug for hairy cell leukemia that has returned or not responded to treatment. About 45 adults with a specific gene mutation (BRAF V600) will take the pills daily in 28-day cycles. The goal is to see if this combination can make the cancer disappear completely and keep it away longer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.