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New drug cocktail targets tough leukemia

NCT ID NCT04324112

First seen Nov 11, 2025 · Last updated Jun 07, 2026 · Updated 31 times

Summary

This study tests whether a combination of two pills (encorafenib and binimetinib) works better than the current drug for hairy cell leukemia that didn't respond to or returned after treatment. About 45 adults with a specific gene mutation (BRAF V600) will take the drugs daily in 28-day cycles. The goal is to see if this combo can shrink or eliminate the cancer more effectively.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-••••

Conditions

The condition(s) this trial relates to.

hairy cell leukemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.