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Which early signs foretell recovery in childhood encephalitis?

NCT ID NCT07830927

NEW Knowledge-focused Sponsor: Assiut University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 21, 2026 · Last updated Sep 21, 2026

Summary

Researchers at Assiut University Children Hospital are tracking 88 children with encephalitis to see which clinical, laboratory, and imaging findings at admission relate to early neurological outcomes. The study measures functional status at discharge using a standard scale, along with length of hospital stay, intensive care needs, and feeding tube requirements. The goal is to identify early predictors that could help doctors anticipate which children may need more support.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If researchers identify which early signs predict recovery, doctors could better tailor monitoring and treatment for children with encephalitis.
What could go wrong
This observational study cannot prove cause and effect, and its findings from one hospital may not apply to other settings or populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 88 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Feb 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Children aged 1 month to 12 years admitted to Assiut University Children Hospital with possible or probable encephalitis according to the International Encephalitis Consortium 2013 case definition.

Ages

1 month to 12 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age from 1 month to 12 years * Possible or probable encephalitis according to the International Encephalitis Consortium 2013 case definition * Written informed consent from parents or legal guardians Exclusion Criteria: * Pre-existing severe neurodisability pediatric modified Rankin Scale greater than or equal to 3 before the index illness * Primary diagnosis of traumatic brain injury or cerebral malaria * Known inborn error of metabolism or neurodegenerative disorder prior to the encephalitis episode * Absence of documented neurologic outcome assessment

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Conditions

The condition(s) this trial relates to.

brain disorder encephalitis Neurologic Manifestations

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Brain diseases Encephalitis Neurologic manifestations

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

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