Autism vs bipolar: scientists compare emotional reactions
NCT ID NCT02423499
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at how adults with autism spectrum disorder (ASD) and bipolar disorder (BD) experience and show emotions. Researchers measured things like heart rate, pupil size, and facial expressions in a lab, and also tracked emotions in daily life for a week. The goal was to find what emotional patterns are unique to each condition and what they share. 90 adults aged 18-50 took part.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 90 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2015
- Finished
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May 2021
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
ASD subjects will be recruited at Centre Universitaire de Pédopsychiatrie, CHRU de Tours, FRANCE. BD subjects will be recruited at Clinique Psychiatrique Universitaire, CHRU de Tours, FRANCE. Healthy volunteers will be recruited at Centre d'Inverstigation Clinique, CHRU de Tours, FRANCE.
- Ages
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18 to 50 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * For all participants: * Age between 18 and 50 years * Normal vision (or corrected) * Absence of neurological disorder (epilepsy , head trauma, ... ) * Ability to understand information about the protocol * Informed and signed consent * normal mood (euthymia) * normal or high intelligence * Subjects with ASD: * Subjects with an autism spectrum disorder according to the DSM-5 * The diagnosis is confirmed by diagnostic interviews: ADI- R (Autism Diagnostic Interview-Revised) and / or ADOS (Autism Diagnostic Observation Schedule ) . * Subjects with bipolar disorder: * Diagnosis of bipolar disorder according to DSM-IV-TR or DSM -5 * The diagnosis is confirmed by the MINI 6.0 (The Mini-International Neuropsychiatric Interview) . * Healthy volunteers: * Inclusion after checking the national register of healthy volunteers * No history of disease of the central nervous system or psychiatric disorder * No family history of ASD or BD in the first degree * Lack of psychotropic medication or current cardiotropic * Lack of psychiatric disorder on Axis I MINI 6.0 * AQ Score \< 32
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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LEMAIRE
Tours, 37044, France
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Other studies related to the condition(s) this trial covers.
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