Sniff test: saliva may reveal your true feelings
NCT ID NCT07320040
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study explores whether smelling different fragrances can trigger emotional responses that show up as measurable molecules in saliva. Researchers will collect saliva samples from 240 healthy adults before and after they smell various scents, measuring hormones like cortisol and oxytocin. The goal is to identify a pattern of biomarkers that could indicate positive or negative emotions, potentially leading to a non-invasive way to assess emotional states.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to a simple saliva test to measure emotional responses, useful for research or mood monitoring.
- What could go wrong
- This is an early observational study, not a treatment trial. The biomarkers may not reliably reflect emotions, and results may not apply to real-world settings.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 240 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2022
- Expected to finish
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Jun 2027
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The population for this study will consist of healthy volunteers who meet the eligibility criteria.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Subject willing to follow study procedures * Subject able to understand the purpose, nature and methodology of the study * Subject has signed informed consent form * Subjects between 18 and 60 years of age. Exclusion Criteria: * Subjects deprived of liberty, protected adults, vulnerable persons or minors * Subjects with a proven or suspected chronic infectious disease that could entail a risk of contamination during sample handling (laboratories not equipped to handle this type of sample) * Rejection to sign the consent form. Non specific inclusion criteria: * Pregnant or breastfeeding women * Subjects presenting anosmia during the last 15 days * Subjects presenting symptoms and signs of active oral inflammation, advanced periodontitis or severe gingivitis.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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SYS2DIAG - UMR9005 CNRS/ALCEN, Montpellier, 34184
RECRUITINGMontpellier, France
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