EMDR vs. pills: which works better for PTSD?
NCT ID NCT06955845
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed study tested two common PTSD treatments head-to-head: EMDR therapy (a talking therapy with eye movements) and SSRI antidepressants. Sixty adults with PTSD were randomly assigned to one treatment for six weeks. Researchers measured how many people achieved symptom remission and whether their quality of life improved.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Eye Movement Desensitization and Reprocessing (EMDR) therapy and selective serotonin reuptake inhibitors (SSRIs)
- What this could lead to
- If EMDR proves as effective as SSRIs, it could offer a drug-free option for managing PTSD symptoms.
- What could go wrong
- This is a small, single-site trial with only 60 participants over 6 weeks, so results may not apply broadly. Both treatments have known limitations and side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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60 people
The number who actually took part.
- Started
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May 2025
- Finished
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Dec 2025
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Age 18-60 years Clinical diagnosis of Post-Traumatic Stress Disorder (PTSD) Duration of illness ≥ 6 months Able to provide informed consent Exclusion Criteria: Current substance abuse or dependence History of psychotic disorder or bipolar disorder Active suicidal ideation Concurrent psychotherapy or psychiatric medication (except study-assigned SSRI)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Combined Military Hospital
Nowshera, KPK, 25770, Pakistan
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Department of Psychiatry, Combined Military Hospital Nowshera
Nowshera, Kpk, 25770, Pakistan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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