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New drug combo aims to tame immune attack after stem cell transplant

NCT ID NCT06996119

First seen May 14, 2026 · Last updated May 24, 2026 · Updated 3 times

Summary

This early-phase trial tests whether adding emapalumab to standard medications can safely prevent graft-versus-host disease (GVHD) in 15 adults with leukemia or myelodysplastic syndrome receiving a reduced-intensity donor stem cell transplant. Emapalumab blocks a protein that drives inflammation, while the other drugs suppress the immune system to protect the patient's body. The study focuses on safety and side effects, not cure.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • City of Hope Medical Center

    RECRUITING

    Duarte, California, 91010, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.