New drug elranatamab tested in Real-World chinese myeloma patients
NCT ID NCT07320326
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study follows 159 Chinese patients with triple-class exposed relapsed/refractory multiple myeloma who are taking elranatamab in routine care. Researchers will track how well the drug controls the cancer, including response rates and survival. The goal is to see if elranatamab works in real-world settings and to improve treatment strategies.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Elranatamab
- What this could lead to
- If successful, this study could confirm that elranatamab works well in Chinese patients with hard-to-treat multiple myeloma, helping doctors use it more effectively.
- What could go wrong
- This is an observational registry, not a controlled trial, so results may be less definitive. It is also early-stage in China, and effectiveness may vary across patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 159 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Dec 2025
An estimate. Start dates often move.
- Expected to finish
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Sep 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Participants with TCE-RRMM who have received or are planning to start Elranatamab treatment according to the local Health Authority approved product label (routine-care). Patients must meet the Inclusion Criteria and the Exclusion Criteria to be eligible for inclusion in the study.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Participants with TCE-RRMM who have received or are planning to start Elranatamab treatment according to the local Health Authority approved product label (routine-care). Patients must meet the following criteria to be eligible for inclusion in the study: In the retrospective part: 1. Male or female patients above 18 years old 2. Patients diagnosed with RRMM(IMWG) 3. Prior lines of therapy must include a proteasome inhibitor, an immunomodulatory drug and anti-CD38 monoclonal antibody in any order during the course of treatment 4. Patients received at least 1 treatment dose of Elranatamab treatment after commercial launch in China and according to the approved product label (routine-care) in China (consistent with the approved label in China)\* 5. Patients understand and voluntarily sign an ICF . In the prospective part: 1. Male or female patients above 18 years old 2. Patients diagnosed with RRMM (IMWG) 3. Prior lines of therapy must include a proteasome inhibitor, an immunomodulatory drug and anti-CD38 monoclonal antibody in any order during the course of treatment 4. Patients treated with elranatamab as monotherapy or a part of combination therapy and according to the approved product label (routine-care) in China (consistent with the approved label in China)\* 5. Patient understand and voluntarily sign an ICF. \*Note: If patients received Elranatamab treatment at a Hong Kong site,the treatment must consist the indications approved in Hong Kong. Exclusion Criteria: Patients meeting the following criteria will not be included in the study: In the retrospective part: 1. Patients with documented diagnosis of other cancers prior to the diagnosis of MM 2. Patients enrolled in interventional clinical trials of any drug for MM treatment 3. Patients with incomplete medical records or missing clinical laboratory data that preclude effectiveness evaluation. 4. Patients who, in the opinion of the investigator, have other factors that make them unsuitable for study participation. In the prospective part: 1. Patients with documented diagnosis of other cancers prior to the diagnosis of MM 2. Patients with contraindication listed in the package insert of elranatamab 3. Patients enrolled in interventional clinical trials of Elranatamab or any other drug for MM treatment
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Peking University People's Hospital
Beijing, Beijing Municipality, 100044, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a tropical tea shrink blood cancers?
- Engineered immune cells take aim at Hard-to-Treat myeloma
- Can engineered immune cells outsmart Treatment-Resistant myeloma?
- Can a lower dose of a myeloma drug keep the disease in check with fewer side effects?
- A pre-treatment pill may supercharge cancer-fighting immune cells