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Promising antibody drug takes on hard-to-treat bone marrow cancer

NCT ID NCT04517851

First seen Nov 01, 2025 · Last updated Jun 13, 2026 · Updated 26 times

Summary

This early study tests whether elotuzumab can help people with a specific type of myelofibrosis, a serious bone marrow disorder. The drug targets a protein on cancer cells to try to improve blood counts, shrink an enlarged spleen, and ease symptoms. The trial includes 15 adults with JAK2-mutated disease who have not responded well to other treatments.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

The condition(s) this trial relates to.

acquired polycythemia vera primary myelofibrosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.