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New drug combo shows promise for aggressive myeloma

NCT ID NCT01668719

Disease control Sponsor: SWOG Cancer Research Network Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested adding elotuzumab to a standard three-drug combination (bortezomib, lenalidomide, dexamethasone) for people newly diagnosed with high-risk multiple myeloma, a blood cancer that tends to come back quickly. The goal was to find the safest dose of elotuzumab and see if the four-drug combo works better at controlling the cancer. The trial included 142 participants and looked at side effects, cancer progression, and survival.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 1/2

Runs two stages together: safety and dose first, then whether the treatment works.

Participants

142 people

The number who actually took part.

Start date

Nov 2012

Finished

Sep 2025

Lead sponsor

A research network

The lead sponsor is a research network or cooperative group.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients must have newly diagnosed active multiple myeloma (MM) * For the Phase II portion only, patients must have high-risk MM based on one or more of the following criteria at the time of initial diagnosis (prior to any chemotherapy): * Poor-risk genomic signature according to the University of Arkansas 70-gene model (available clinically as myeloma prognostic risk score \[MyPRS\] score, Signal Genetics, Inc) AND/OR * Translocation (14;16), and/or translocation (14;20), and/or deletion (17p) by fluorescence in-situ hybridization (FISH) or cytogenetics AND/OR * Primary plasma cell leukemia (defined by either \>= 2,000 plasma cells/mL of peripheral blood, or 20% on a manual differential count) AND/OR * Serum lactate dehydrogenase (LDH) \>= 2 x institutional upper limit of normal (IULN) AND/OR * 1q21 amplification by FISH analysis AND/OR * High risk by the SKY92 signature * Patients with non-secretory MM or known amyloidosis are not eligible * Patients must have measurable disease within 28 days prior to registration (or prior to initiation of first induction course for patients with prior therapy) * Patients on the Phase I portion may not have received ANY prior chemotherapy; patients on the Phase II portion may have received one prior cycle of any non-investigational chemotherapy; prior chemotherapy must have been completed within 56 days prior to registration and all toxicities must have resolved to =\< grade 1; patients on either portion may have received prior treatment with dexamethasone, providing total number of days of treatment was =\< 14 days and total treatment dose was =\< 360 mg * Patients may have received prior radiotherapy for symptomatic localized bone lesions or impending spinal cord compression only; radiotherapy must be completed at least 14 days prior to registration and all toxicities must have resolved to =\< grade 1 * Absolute neutrophil count (ANC) \>= 1,000 cells/mm\^3 without growth factor support * Platelet count \>= 70,000 cells/mm\^3 for patients who have bone marrow plasmacytosis \< 50%; or \>= 50,000 cells/mm\^3 for patients who have bone marrow plasmacytosis of \>= 50% * Total bilirubin =\< 1.5 x institutional upper limit of normal (IULN) * Serum glutamic oxaloacetic transaminase (SGOT)/aspartate aminotransferase (AST) and serum glutamate pyruvate transaminase (SGPT)/alanine aminotransferase (ALT) =\< 2.5 x IULN * Creatinine clearance (CrCL) \>= 30 mL/min, measured by a 24-hour urine collection or estimated by the Cockcroft and Gault formula within 14 days prior to registration * Patients must not have active involvement of the central nervous system (CNS) with MM (by clinical evaluation); patients with documentation of, or clinical signs or symptoms consistent with, CNS involvement of MM must have a lumbar puncture that is negative for CNS involvement of MM; the lumbar puncture must be completed within 14 days prior to registration; patients with no previous history of documented CNS involvement and with no clinical signs or symptoms consistent with CNS involvement are not required to have completed a lumbar puncture prior to registration; note that monitoring of CNS involvement and treatment with intrathecal therapy is recommended during protocol treatment * Patients who are known to be human immunodeficiency virus positive (HIV+) are eligible providing they meet all of the following additional criteria within 28 days prior to registration: * Cluster of differentiation (CD)4 cells \>= 500/mm\^3 * Viral load of \< 50 copies HIV messenger ribonucleic acid (mRNA)/mm\^3 if on combination antiretroviral therapy (cART) or \< 25,000 copies HIV mRNA if not on cART * No zidovudine or stavudine as part of cART * Patients who are HIV+ and do not meet all of these criteria are not eligible for this study * Patients must have baseline skeletal survey (whole body x-ray) to document lytic lesions, osteopenia or compression fracture * Patients must have Zubrod performance status =\< 2 * Patients with known hepatitis B or hepatitis C infection may be eligible providing they have viral load \< 800,000 IU/L within 28 days prior to registration * Patients must not have POEMS syndrome (plasma cell dyscrasia with polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, and skin changes) * Patients must not have clinically significant illness including uncontrolled, active infection requiring intravenous antibiotics, New York Heart Association (NYHA) class III or class IV heart failure, unstable angina pectoris, myocardial infarction within the past 6 months, uncontrolled \>= grade 3 cardiac arrhythmias, uncontrolled hypertension, or uncontrolled diabetes mellitus; patients must have undergone an electrocardiogram (EKG) within 28 days prior to registration * Uncontrolled diabetes: a glycated hemoglobin (Hg A1C) \> 7% within 14 days prior to registration; the same criterion will be used in patients with confirmed diagnosis of diabetes mellitus who have been on a stable dietary or therapeutic regimen for this condition in the last three months * Uncontrolled blood pressure and hypertension: systolic blood pressure (SBP) \> 140 mm Hg or diastolic blood pressure (DBP) \> 90 mm Hg within 14 days prior to registration; patients are permitted to be receiving multiple anti-hypertensive medications (unless otherwise indicated in the study); all blood pressure measurements within the 14 days prior to registration and on day 1 of cycle 1 must be SBP =\< 140 and DBP =\< 90; an exception can be made by a healthcare provider for a patient with a single blood pressure elevation who upon rechecking has a normal blood pressure * Patients must have history and physical examination within 28 days prior to registration * Patients must not have any psychiatric illness that could potentially interfere with the completion of treatment according to this protocol * Females of childbearing potential (FCBP) must have a negative serum or urine pregnancy test with a sensitivity of at least 25 mIU/mL within 10 - 14 days prior to registration; (Note: that pregnancy testing is also required within 24 hours prior to treatment on cycle 1, day 1); furthermore, they must either commit to continued abstinence from heterosexual intercourse or begin TWO acceptable methods of birth control: one highly effective method and one additional effective method AT THE SAME TIME, at least 28 days before starting lenalidomide; FCBP must also agree to ongoing pregnancy testing; men must agree to use a latex condom during sexual contact with a FCBP, even if they have had a successful vasectomy; a FCBP is a sexually mature woman who: 1) has not undergone a hysterectomy or bilateral oophorectomy; or 2) has not been naturally postmenopausal for at least 24 consecutive months (i.e., has had menses at any time in the preceding 24 consecutive months) * No other prior malignancy is allowed except for the following: adequately treated basal cell or squamous cell skin cancer, in situ cervical cancer, adequately treated stage I or II cancer from which the patient is currently in complete remission, or any other cancer from which the patient has been disease free for five years * Patients must be offered participation in banking of specimens for future research; with the patient's consent, specimens (serum and bone marrow biopsy core) must be submitted to the repository; patient consent must be obtained before specimens are submitted * Patients must be registered to the mandatory Revlimid Risk Evaluation and Mitigation Strategy (REMS)™ program and must be willing and able to comply with the requirements of the Revlimid REMS™ program * Patients or their legally authorized representative must be informed of the investigational nature of this study and must sign and give written informed consent in accordance with institutional and federal guidelines * As a part of the Oncology Patient Enrollment Network (OPEN) registration process the treating institution's identity is provided in order to ensure that the current (within 365 days) date of institutional review board approval for this study has been entered in the system

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Conditions

The condition(s) this trial relates to.

plasma cell myeloma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DS stage I plasma cell myeloma DS stage II plasma cell myeloma DS stage III plasma cell myeloma

Contacts and locations

Locations

  • 21st Century Oncology

    Las Vegas, Nevada, 89109, United States

  • 21st Century Oncology - Fort Apache

    Las Vegas, Nevada, 89148, United States

  • 21st Century Oncology - Henderson

    Henderson, Nevada, 89074, United States

  • 21st Century Oncology - Vegas Tenaya

    Las Vegas, Nevada, 89182, United States

  • Abbott-Northwestern Hospital

    Minneapolis, Minnesota, 55407, United States

  • Adena Regional Medical Center

    Chillicothe, Ohio, 45601, United States

  • Alaska Breast Care and Surgery LLC

    Anchorage, Alaska, 99508, United States

  • Alaska Women's Cancer Care

    Anchorage, Alaska, 99508, United States

  • Alegent Health Bergan Mercy Medical Center

    Omaha, Nebraska, 68124, United States

  • Alegent Health Immanuel Medical Center

    Omaha, Nebraska, 68122, United States

  • Alegent Health Lakeside Hospital

    Omaha, Nebraska, 68130, United States

  • Allegiance Health

    Jackson, Michigan, 49201, United States

  • Anchorage Oncology Centre

    Anchorage, Alaska, 99508, United States

  • Atrium Medical Center-Middletown Regional Hospital

    Franklin, Ohio, 45005-1066, United States

  • Aurora BayCare Medical Center

    Green Bay, Wisconsin, 54311, United States

  • Aurora Cancer Care-Grafton

    Grafton, Wisconsin, 53024, United States

  • Aurora Cancer Care-Kenosha South

    Kenosha, Wisconsin, 53142, United States

  • Aurora Cancer Care-Milwaukee

    Milwaukee, Wisconsin, 53209, United States

  • Aurora Cancer Care-Milwaukee West

    Wauwatosa, Wisconsin, 53226, United States

  • Aurora Cancer Care-Racine

    Racine, Wisconsin, 53406, United States

  • Aurora Cancer Care-Southern Lakes VLCC

    Burlington, Wisconsin, 53105, United States

  • Aurora Cancer Care-Waukesha

    Waukesha, Wisconsin, 53188, United States

  • Aurora Health Care Germantown Health Center

    Germantown, Wisconsin, 53022, United States

  • Aurora Health Center-Fond du Lac

    Fond du Lac, Wisconsin, 54937, United States

  • Aurora Medical Center in Summit

    Summit, Wisconsin, 53066, United States

  • Aurora Saint Luke's Medical Center

    Milwaukee, Wisconsin, 53215, United States

  • Aurora Sinai Medical Center

    Milwaukee, Wisconsin, 53233, United States

  • Aurora West Allis Medical Center

    West Allis, Wisconsin, 53227, United States

  • Bay Area Medical Center

    Marinette, Wisconsin, 54143, United States

  • Beaumont Hospital-Dearborn

    Dearborn, Michigan, 48124, United States

  • Beebe Health Campus

    Rehoboth Beach, Delaware, 19971, United States

  • Beebe Medical Center

    Lewes, Delaware, 19958, United States

  • Bixby Medical Center

    Adrian, Michigan, 49221, United States

  • Blanchard Valley Hospital

    Findlay, Ohio, 45840, United States

  • Borgess Medical Center

    Kalamazoo, Michigan, 49001, United States

  • Bronson Battle Creek

    Battle Creek, Michigan, 49017, United States

  • Bronson Methodist Hospital

    Kalamazoo, Michigan, 49007, United States

  • Cancer Care Center of Decatur

    Decatur, Illinois, 62526, United States

  • Cancer Care Specialists of Illinois-Swansea

    Swansea, Illinois, 62226, United States

  • Cancer Center of Western Wisconsin

    New Richmond, Wisconsin, 54017, United States

  • Cancer Research Consortium of West Michigan NCORP

    Grand Rapids, Michigan, 49503, United States

  • Cancer Research for the Ozarks NCORP

    Springfield, Missouri, 65804, United States

  • Cancer Therapy and Integrative Medicine

    Las Vegas, Nevada, 89121, United States

  • Cancer and Blood Specialists-Henderson

    Henderson, Nevada, 89052, United States

  • Cancer and Blood Specialists-Shadow

    Las Vegas, Nevada, 89106, United States

  • Cancer and Blood Specialists-Tenaya

    Las Vegas, Nevada, 89128, United States

  • Capital Region Medical Center-Goldschmidt Cancer Center

    Jefferson City, Missouri, 65109, United States

  • Carolinas HealthCare System NorthEast

    Concord, North Carolina, 28025, United States

  • Carolinas HealthCare System Union

    Monroe, North Carolina, 28112, United States

  • Carolinas Medical Center/Levine Cancer Institute

    Charlotte, North Carolina, 28203, United States

  • Case Western Reserve University

    Cleveland, Ohio, 44106, United States

  • Castle Medical Center

    Kailua, Hawaii, 96734, United States

  • Centerpoint Medical Center LLC

    Independence, Missouri, 64057, United States

  • Central Care Cancer Center-Carrie J Babb Cancer Center

    Bolivar, Missouri, 65613, United States

  • Central Illinois Hematology Oncology Center

    Springfield, Illinois, 62702, United States

  • Centralia Oncology Clinic

    Centralia, Illinois, 62801, United States

  • Charlotte Hungerford Hospital Center for Cancer Care

    Torrington, Connecticut, 06790, United States

  • Christiana Care Health System-Christiana Hospital

    Newark, Delaware, 19718, United States

  • Christiana Care Health System-Wilmington Hospital

    Wilmington, Delaware, 19801, United States

  • Christiana Gynecologic Oncology LLC

    Newark, Delaware, 19713, United States

  • City of Hope Comprehensive Cancer Center

    Duarte, California, 91010, United States

  • Clackamas Radiation Oncology Center

    Clackamas, Oregon, 97015, United States

  • Cleveland Clinic Cancer Center Beachwood

    Beachwood, Ohio, 44122, United States

  • Cleveland Clinic Cancer Center Independence

    Independence, Ohio, 44131, United States

  • Cleveland Clinic Cancer Center Mansfield

    Mansfield, Ohio, 44906, United States

  • Cleveland Clinic Cancer Center Strongsville

    Strongsville, Ohio, 44136, United States

  • Cleveland Clinic Cancer Center/Fairview Hospital

    Cleveland, Ohio, 44111, United States

  • Cleveland Clinic Foundation

    Cleveland, Ohio, 44195, United States

  • Cleveland Clinic Wooster Family Health and Surgery Center

    Wooster, Ohio, 44691, United States

  • Columbus NCI Community Oncology Research Program

    Columbus, Ohio, 43215, United States

  • Columbus Oncology and Hematology Associates Inc

    Columbus, Ohio, 43214, United States

  • Compass Oncology Vancouver

    Vancouver, Washington, 98684, United States

  • Comprehensive Cancer Centers of Nevada

    Las Vegas, Nevada, 89148, United States

  • Comprehensive Cancer Centers of Nevada - Central Valley

    Las Vegas, Nevada, 89169, United States

  • Comprehensive Cancer Centers of Nevada - Henderson

    Henderson, Nevada, 89052, United States

  • Comprehensive Cancer Centers of Nevada - Northwest

    Las Vegas, Nevada, 89128, United States

  • Comprehensive Cancer Centers of Nevada-Southeast Henderson

    Henderson, Nevada, 89074, United States

  • Comprehensive Cancer Centers of Nevada-Summerlin

    Las Vegas, Nevada, 89144, United States

  • Constantinou, Costas L MD (UIA Investigator)

    Bettendorf, Iowa, 52722, United States

  • Cotton O'Neil Cancer Center / Stormont Vail Health

    Topeka, Kansas, 66606, United States

  • CoxHealth Cancer Center

    Branson, Missouri, 65616, United States

  • CoxHealth South Hospital

    Springfield, Missouri, 65807, United States

  • Creighton University Medical Center

    Omaha, Nebraska, 68131, United States

  • Crossroads Cancer Center

    Effingham, Illinois, 62401, United States

  • Decatur Memorial Hospital

    Decatur, Illinois, 62526, United States

  • Delaware Clinical and Laboratory Physicians PA

    Newark, Delaware, 19713, United States

  • Delaware Health Center-Grady Cancer Center

    Delaware, Ohio, 43015, United States

  • Delaware Radiation Oncology

    Delaware, Ohio, 43015, United States

  • Delbert Day Cancer Institute at PCRMC

    Rolla, Missouri, 65401, United States

  • Diagnostic and Treatment Center

    Weston, Wisconsin, 54476, United States

  • Doctors Hospital

    Columbus, Ohio, 43228, United States

  • Essentia Health Cancer Center

    Duluth, Minnesota, 55805, United States

  • Essentia Health Saint Mary's Medical Center

    Duluth, Minnesota, 55805, United States

  • Fairfield Medical Center

    Lancaster, Ohio, 43130, United States

  • Fairview Ridges Hospital

    Burnsville, Minnesota, 55337, United States

  • Fairview-Southdale Hospital

    Edina, Minnesota, 55435, United States

  • Faith Regional Medical Offices West

    Norfolk, Nebraska, 68701, United States

  • FirstHealth of the Carolinas-Moore Regional Hosiptal

    Pinehurst, North Carolina, 28374, United States

  • Flower Hospital

    Sylvania, Ohio, 43560, United States

  • Fredericksburg Oncology Inc

    Fredericksburg, Virginia, 22401, United States

  • Fulton County Health Center

    Wauseon, Ohio, 43567, United States

  • Garneau, Stewart C MD (UIA Investigator)

    Moline, Illinois, 61265, United States

  • Geaugra Hospital

    Chardon, Ohio, 44024, United States

  • Geisinger Medical Center

    Danville, Pennsylvania, 17822, United States

  • Geisinger Medical Center-Cancer Center Hazleton

    Hazleton, Pennsylvania, 18201, United States

  • Geisinger Medical Group

    State College, Pennsylvania, 16801, United States

  • Geisinger Medical Oncology-Lewisburg

    Lewisburg, Pennsylvania, 17837, United States

  • Geisinger Medical Oncology-Pottsville

    Pottsville, Pennsylvania, 17901, United States

  • Geisinger Wyoming Valley/Henry Cancer Center

    Wilkes-Barre, Pennsylvania, 18711, United States

  • Genesis Healthcare System Cancer Care Center

    Zanesville, Ohio, 43701, United States

  • Genesys Hurley Cancer Institute

    Flint, Michigan, 48503, United States

  • Good Samaritan Hospital - Dayton

    Dayton, Ohio, 45406, United States

  • Good Samaritan Regional Health Center

    Mount Vernon, Illinois, 62864, United States

  • Grady Memorial Hospital

    Delaware, Ohio, 43015, United States

  • Grant Medical Center

    Columbus, Ohio, 43215, United States

  • Great Plains Regional Medical Center

    North Platte, Nebraska, 69103, United States

  • Green Bay Oncology - Escanaba

    Escanaba, Michigan, 49829, United States

  • Green Bay Oncology - Iron Mountain

    Iron Mountain, Michigan, 49801, United States

  • Green Bay Oncology - Oconto Falls

    Oconto Falls, Wisconsin, 54154, United States

  • Green Bay Oncology - Sturgeon Bay

    Sturgeon Bay, Wisconsin, 54235, United States

  • Green Bay Oncology Limited at Saint Mary's Hospital

    Green Bay, Wisconsin, 54303, United States

  • Green Bay Oncology at Saint Vincent Hospital

    Green Bay, Wisconsin, 54301-3526, United States

  • Gundersen Lutheran Medical Center

    La Crosse, Wisconsin, 54601, United States

  • HSHS Saint Nicholas Hospital

    Sheboygan, Wisconsin, 53081, United States

  • Hawaii Cancer Care Inc-Liliha

    Honolulu, Hawaii, 96817, United States

  • Hawaii Cancer Care Inc-POB II

    Honolulu, Hawaii, 96813, United States

  • Hawaii Oncology Inc-Kuakini

    Honolulu, Hawaii, 96817, United States

  • Hawaii Oncology Inc-Pali Momi

    ‘Aiea, Hawaii, 96701, United States

  • Hays Medical Center

    Hays, Kansas, 67601, United States

  • Health Partners Inc

    Minneapolis, Minnesota, 55454, United States

  • HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills

    Las Vegas, Nevada, 89149, United States

  • HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway

    Las Vegas, Nevada, 89109, United States

  • HealthCare Partners Medical Group Oncology/Hematology-San Martin

    Las Vegas, Nevada, 89113, United States

  • HealthCare Partners Medical Group Oncology/Hematology-Tenaya

    Las Vegas, Nevada, 89128, United States

  • Heartland Hematology and Oncology Associates Incorporated

    Kansas City, Missouri, 64118, United States

  • Heartland Regional Medical Center

    Saint Joseph, Missouri, 64506, United States

  • Helen F Graham Cancer Center

    Newark, Delaware, 19713, United States

  • Hematology/Oncology Clinic LLP

    Baton Rouge, Louisiana, 70809, United States

  • Hennepin County Medical Center

    Minneapolis, Minnesota, 55415, United States

  • Hickman Cancer Center

    Adrian, Michigan, 49221, United States

  • Hillcrest Hospital Cancer Center

    Mayfield Heights, Ohio, 44124, United States

  • Hines Veterans Administration Hospital

    Hines, Illinois, 60141, United States

  • Holy Family Memorial Hospital

    Manitowoc, Wisconsin, 54221, United States

  • Hurley Medical Center

    Flint, Michigan, 48502, United States

  • Hutchinson Area Health Care

    Hutchinson, Minnesota, 55350, United States

  • Illinois CancerCare-Bloomington

    Bloomington, Illinois, 61704, United States

  • Illinois CancerCare-Canton

    Canton, Illinois, 61520, United States

  • Illinois CancerCare-Carthage

    Carthage, Illinois, 62321, United States

  • Illinois CancerCare-Eureka

    Eureka, Illinois, 61530, United States

  • Illinois CancerCare-Galesburg

    Galesburg, Illinois, 61401, United States

  • Illinois CancerCare-Kewanee Clinic

    Kewanee, Illinois, 61443, United States

  • Illinois CancerCare-Macomb

    Macomb, Illinois, 61455, United States

  • Illinois CancerCare-Ottawa Clinic

    Ottawa, Illinois, 61350, United States

  • Illinois CancerCare-Pekin

    Pekin, Illinois, 61554, United States

  • Illinois CancerCare-Peoria

    Peoria, Illinois, 61615, United States

  • Illinois CancerCare-Peru

    Peru, Illinois, 61354, United States

  • Illinois CancerCare-Princeton

    Princeton, Illinois, 61356, United States

  • Ingalls Memorial Hospital

    Harvey, Illinois, 60426, United States

  • Iredell Memorial Hospital

    Statesville, North Carolina, 28677, United States

  • Ireland Cancer Center Landerbrook Health Center

    Mayfield Heights, Ohio, 44124, United States

  • Ireland Cancer Center at Firelands Regional Medical Center

    Sandusky, Ohio, 44870, United States

  • Kansas City NCI Community Oncology Research Program

    Prairie Village, Kansas, 66208, United States

  • Kansas Institute of Medicine Cancer and Blood Center

    Lenexa, Kansas, 66219, United States

  • Kapiolani Medical Center for Women and Children

    Honolulu, Hawaii, 96826, United States

  • Katmai Oncology Group

    Anchorage, Alaska, 99508, United States

  • Kettering Medical Center

    Kettering, Ohio, 45429, United States

  • Kinston Medical Specialists PA

    Kinston, North Carolina, 28501, United States

  • Knox Community Hospital

    Mount Vernon, Ohio, 43050, United States

  • Lake Huron Medical Center

    Port Huron, Michigan, 48060, United States

  • Lake Region Healthcare Corporation-Cancer Care

    Fergus Falls, Minnesota, 56537, United States

  • Lake University Ireland Cancer Center

    Mentor, Ohio, 44060, United States

  • Lakeland Community Hospital

    Niles, Michigan, 49120, United States

  • Lakeland Hospital

    Saint Joseph, Michigan, 49085, United States

  • Lakeview Hospital

    Stillwater, Minnesota, 55082, United States

  • Lakeview Medical Center-Marshfield Clinic

    Rice Lake, Wisconsin, 54868, United States

  • Lancaster Radiation Oncology

    Lancaster, Ohio, 43130, United States

  • Las Vegas Cancer Center-Henderson

    Henderson, Nevada, 89052, United States

  • Las Vegas Cancer Center-Medical Center

    Las Vegas, Nevada, 89148-2405, United States

  • Lawrence Memorial Hospital

    Lawrence, Kansas, 66044, United States

  • Legacy Good Samaritan Hospital and Medical Center

    Portland, Oregon, 97210, United States

  • Legacy Meridian Park Hospital

    Tualatin, Oregon, 97062, United States

  • Legacy Mount Hood Medical Center

    Gresham, Oregon, 97030, United States

  • Legacy Salmon Creek Hospital

    Vancouver, Washington, 98686, United States

  • Lewistown Hospital

    Lewistown, Pennsylvania, 17044, United States

  • Liberty Radiation Oncology Center

    Liberty, Missouri, 64068, United States

  • Licking Memorial Hospital

    Newark, Ohio, 43055, United States

  • Lima Memorial Hospital

    Lima, Ohio, 45804, United States

  • Los Angeles County-USC Medical Center

    Los Angeles, California, 90033, United States

  • Loyola University Medical Center

    Maywood, Illinois, 60153, United States

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Marie Yeager Cancer Center

    Saint Joseph, Michigan, 49085, United States

  • Marietta Memorial Hospital

    Marietta, Ohio, 45750, United States

  • Marshfield Clinic

    Marshfield, Wisconsin, 54449, United States

  • Marshfield Clinic - Weston Center

    Weston, Wisconsin, 54476, United States

  • Marshfield Clinic - Wisconsin Rapids Center

    Wisconsin Rapids, Wisconsin, 54494, United States

  • Marshfield Clinic Cancer Care at Saint Michael's Hospital

    Stevens Point, Wisconsin, 54481, United States

  • Marshfield Clinic Cancer Center at Sacred Heart

    Eau Claire, Wisconsin, 54701, United States

  • Marshfield Clinic at James Beck Cancer Center

    Rhinelander, Wisconsin, 54501, United States

  • Marshfield Clinic-Chippewa Center

    Chippewa Falls, Wisconsin, 54729, United States

  • Marshfield Clinic-Minocqua Center

    Minocqua, Wisconsin, 54548, United States

  • Marshfield Clinic-Rice Lake Center

    Rice Lake, Wisconsin, 54868, United States

  • Marshfield Clinic-Wausau Center

    Wausau, Wisconsin, 54401, United States

  • Mary Greeley Medical Center

    Ames, Iowa, 50010, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Mayo Clinic in Florida

    Jacksonville, Florida, 32224-9980, United States

  • McFarland Clinic PC-Boone

    Boone, Iowa, 50036, United States

  • McFarland Clinic PC-Jefferson

    Jefferson, Iowa, 50129, United States

  • McFarland Clinic PC-Marshalltown

    Marshalltown, Iowa, 50158, United States

  • McFarland Clinic PC-Trinity Cancer Center

    Fort Dodge, Iowa, 50501, United States

  • McFarland Clinic PC-William R Bliss Cancer Center

    Ames, Iowa, 50010, United States

  • McLeod Regional Medical Center

    Florence, South Carolina, 29506, United States

  • Medical Oncology Hematology Consultants PA

    Newark, Delaware, 19713, United States

  • Medical Oncology and Hematology Group PC-Guilford

    Guilford, Connecticut, 06437, United States

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

  • Memorial Hospital Of Martinsville

    Martinsville, Virginia, 24115, United States

  • Memorial Hospital of Carbondale

    Carbondale, Illinois, 62902, United States

  • Memorial Medical Center

    Springfield, Illinois, 62781, United States

  • Menorah Medical Center

    Overland Park, Kansas, 66209, United States

  • Mercy Cancer Center-Elyria

    Elyria, Ohio, 44035, United States

  • Mercy Health Mercy Campus

    Muskegon, Michigan, 49444, United States

  • Mercy Health Saint Mary's

    Grand Rapids, Michigan, 49503, United States

  • Mercy Hospital

    Coon Rapids, Minnesota, 55433, United States

  • Mercy Hospital Saint Louis

    St Louis, Missouri, 63141, United States

  • Mercy Hospital Springfield

    Springfield, Missouri, 65804, United States

  • Mercy Hospital of Tiffin

    Tiffin, Ohio, 44883, United States

  • Mercy Medical Center-Sioux City

    Sioux City, Iowa, 51104, United States

  • Mercy Memorial Hospital

    Monroe, Michigan, 48162, United States

  • Mercy Saint Anne Hospital

    Toledo, Ohio, 43623, United States

  • Methodist Medical Center of Illinois

    Peoria, Illinois, 61603, United States

  • Metro Minnesota Community Oncology Research Consortium

    Saint Louis Park, Minnesota, 55416, United States

  • Miami Valley Hospital

    Dayton, Ohio, 45409, United States

  • Miami Valley Hospital South

    Centerville, Ohio, 45459, United States

  • Michigan Cancer Research Consortium NCORP

    Ann Arbor, Michigan, 48106, United States

  • Miller-Dwan Hospital

    Duluth, Minnesota, 55805, United States

  • Minimally Invasive Surgery Hospital

    Lenexa, Kansas, 66219, United States

  • Minnesota Oncology Hematology PA-Maplewood

    Maplewood, Minnesota, 55109, United States

  • Minnesota Oncology Hematology PA-Woodbury

    Woodbury, Minnesota, 55125, United States

  • Missouri Baptist Medical Center

    St Louis, Missouri, 63131, United States

  • Missouri Baptist Outpatient Center-Sunset Hills

    Sunset Hills, Missouri, 63127, United States

  • Missouri Baptist Sullivan Hospital

    Sullivan, Missouri, 63080, United States

  • Missouri Valley Cancer Consortium

    Omaha, Nebraska, 68106, United States

  • Mount Carmel East Hospital

    Columbus, Ohio, 43213, United States

  • Mount Carmel Health Center West

    Columbus, Ohio, 43222, United States

  • Munson Medical Center

    Traverse City, Michigan, 49684, United States

  • Nanticoke Memorial Hospital

    Seaford, Delaware, 19973, United States

  • Nebraska Cancer Research Center

    Lincoln, Nebraska, 68510, United States

  • Nebraska Hematology and Oncology

    Lincoln, Nebraska, 68506, United States

  • Nevada Cancer Research Foundation CCOP

    Las Vegas, Nevada, 89106, United States

  • Nevada Cancer Specialists-Fort Apache

    Las Vegas, Nevada, 89148, United States

  • New Ulm Medical Center

    New Ulm, Minnesota, 56073, United States

  • Newark Radiation Oncology

    Newark, Ohio, 43055, United States

  • Newman Regional Health

    Emporia, Kansas, 66801, United States

  • North Coast Cancer Care

    Sandusky, Ohio, 44870, United States

  • North Kansas City Hospital

    Kansas City, Missouri, 64116, United States

  • North Memorial Medical Health Center

    Robbinsdale, Minnesota, 55422, United States

  • OSF Saint Francis Medical Center

    Peoria, Illinois, 61637, United States

  • OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center

    Pekin, Illinois, 61554, United States

  • OSF Saint Francis Radiation Oncology at Peoria Cancer Center

    Peoria, Illinois, 61615, United States

  • OhioHealth Mansfield Hospital

    Mansfield, Ohio, 44903, United States

  • Olathe Medical Center

    Olathe, Kansas, 66061, United States

  • Oncology Hematology Care Inc - Anderson

    Cincinnati, Ohio, 45230, United States

  • Oncology Hematology Care Inc-Blue Ash

    Cincinnati, Ohio, 45242, United States

  • Oncology Hematology Care Inc-Crestview

    Crestview Hills, Kentucky, 41017, United States

  • Oncology Hematology Care Inc-Eden Park

    Cincinnati, Ohio, 45202, United States

  • Oncology Hematology Care Inc-Healthplex

    Fairfield, Ohio, 45014, United States

  • Oncology Hematology Care Inc-Kenwood

    Cincinnati, Ohio, 45236, United States

  • Oncology Hematology Care Inc-Mercy West

    Cincinnati, Ohio, 45211, United States

  • Oncology Hematology West

    Omaha, Nebraska, 68124, United States

  • Oncology Hematology West PC

    Omaha, Nebraska, 68130, United States

  • OneHealth Marion General Hospital

    Marion, Ohio, 43302, United States

  • Orange Regional Medical Center

    Middletown, New York, 10940, United States

  • Pali Momi Medical Center

    ‘Aiea, Hawaii, 96701, United States

  • Park Nicollet Clinic - Saint Louis Park

    Saint Louis Park, Minnesota, 55416, United States

  • Parkland Health Center-Bonne Terre

    Bonne Terre, Missouri, 63628, United States

  • PeaceHealth Saint John Medical Center

    Longview, Washington, 98632, United States

  • PeaceHealth Southwest Medical Center

    Vancouver, Washington, 98664, United States

  • Porubcin, Michael MD (UIA Investigator)

    Moline, Illinois, 61265, United States

  • Providence Alaska Medical Center

    Anchorage, Alaska, 99508, United States

  • Providence Hospital-Southfield Cancer Center

    Southfield, Michigan, 48075, United States

  • Providence Medical Center

    Kansas City, Kansas, 66112, United States

  • Providence Milwaukie Hospital

    Milwaukie, Oregon, 97222, United States

  • Providence Newberg Medical Center

    Newberg, Oregon, 97132, United States

  • Providence Oncology and Hematology Care Southeast

    Clackamas, Oregon, 97015, United States

  • Providence Portland Medical Center

    Portland, Oregon, 97213, United States

  • Providence Saint Joseph Medical Center/Disney Family Cancer Center

    Burbank, California, 91505, United States

  • Providence Saint Vincent Medical Center

    Portland, Oregon, 97225, United States

  • Providence Willamette Falls Medical Center

    Oregon City, Oregon, 97045, United States

  • Queen's Medical Center

    Honolulu, Hawaii, 96813, United States

  • Radiation Oncology Centers of Nevada Central

    Las Vegas, Nevada, 89106, United States

  • Radiation Oncology Centers of Nevada Southeast

    Las Vegas, Nevada, 89119, United States

  • Radiation Oncology of Northern Illinois

    Ottawa, Illinois, 61350, United States

  • Rapid City Regional Hospital

    Rapid City, South Dakota, 57701, United States

  • Regional Hematology and Oncology PA

    Newark, Delaware, 19713, United States

  • Regional West Medical Center

    Scottsbluff, Nebraska, 69361, United States

  • Regions Hospital

    Saint Paul, Minnesota, 55101, United States

  • Reid Health

    Richmond, Indiana, 47374, United States

  • Research Medical Center

    Kansas City, Missouri, 64132, United States

  • Rice Memorial Hospital

    Willmar, Minnesota, 56201, United States

  • Ridgeview Medical Center

    Waconia, Minnesota, 55387, United States

  • Riverside Methodist Hospital

    Columbus, Ohio, 43214, United States

  • Roger Maris Cancer Center

    Fargo, North Dakota, 58122, United States

  • Saint Alphonsus Cancer Care Center-Boise

    Boise, Idaho, 83706, United States

  • Saint Ann's Hospital

    Westerville, Ohio, 43081, United States

  • Saint Catherine Hospital

    Garden City, Kansas, 67846, United States

  • Saint Charles Hospital

    Oregon, Ohio, 43616, United States

  • Saint Francis Hospital and Medical Center - Topeka

    Topeka, Kansas, 66606, United States

  • Saint Francis Medical Center

    Cape Girardeau, Missouri, 63703, United States

  • Saint Francis Regional Medical Center

    Shakopee, Minnesota, 55379, United States

  • Saint John Hospital and Medical Center

    Detroit, Michigan, 48236, United States

  • Saint John Macomb-Oakland Hospital

    Warren, Michigan, 48093, United States

  • Saint John's Clinic-Rolla-Cancer and Hematology

    Rolla, Missouri, 65401, United States

  • Saint John's Hospital - Healtheast

    Maplewood, Minnesota, 55109, United States

  • Saint Joseph Medical Center

    Bloomington, Illinois, 61701, United States

  • Saint Joseph Mercy Hospital

    Ann Arbor, Michigan, 48106-0995, United States

  • Saint Joseph Mercy Oakland

    Pontiac, Michigan, 48341, United States

  • Saint Joseph Oncology Inc

    Saint Joseph, Missouri, 64507, United States

  • Saint Louis Cancer and Breast Institute-South City

    St Louis, Missouri, 63109, United States

  • Saint Luke's East - Lee's Summit

    Lee's Summit, Missouri, 64086, United States

  • Saint Luke's Hospital of Kansas City

    Kansas City, Missouri, 64111, United States

  • Saint Luke's Regional Medical Center

    Sioux City, Iowa, 51104, United States

  • Saint Luke's South Hospital

    Overland Park, Kansas, 66213, United States

  • Saint Mary Mercy Hospital

    Livonia, Michigan, 48154, United States

  • Saint Mary's of Michigan

    Saginaw, Michigan, 48601, United States

  • Saint Rose Ambulatory and Surgery Center

    Great Bend, Kansas, 67530, United States

  • Saint Vincent Hospital Cancer Center Green Bay

    Green Bay, Wisconsin, 54301, United States

  • Saint Vincent Hospital Cancer Center at Saint Mary's

    Green Bay, Wisconsin, 54303, United States

  • Saint Vincent Mercy Medical Center

    Toledo, Ohio, 43608, United States

  • Sainte Genevieve County Memorial Hospital

    Sainte Genevieve, Missouri, 63670, United States

  • Salina Regional Health Center

    Salina, Kansas, 67401, United States

  • Samaritan North Health Center

    Dayton, Ohio, 45415, United States

  • Sanford Bismarck Medical Center

    Bismarck, North Dakota, 58501, United States

  • Sanford Cancer Center-Oncology Clinic

    Sioux Falls, South Dakota, 57104, United States

  • Sanford Clinic North-Bemidgi

    Bemidji, Minnesota, 56601, United States

  • Sanford Clinic North-Fargo

    Fargo, North Dakota, 58122, United States

  • Sanford Medical Center-Fargo

    Fargo, North Dakota, 58122, United States

  • Sanford USD Medical Center - Sioux Falls

    Sioux Falls, South Dakota, 57117-5134, United States

  • Self Regional Healthcare

    Greenwood, South Carolina, 29646, United States

  • Sinai Hospital of Baltimore

    Baltimore, Maryland, 21215, United States

  • Siouxland Regional Cancer Center

    Sioux City, Iowa, 51101, United States

  • Smilow Cancer Hospital Care Center at Saint Francis

    Hartford, Connecticut, 06105, United States

  • Smilow Cancer Hospital Care Center-Fairfield

    Fairfield, Connecticut, 06824, United States

  • Smilow Cancer Hospital Care Center-Trumbull

    Trumbull, Connecticut, 06611, United States

  • Smilow Cancer Hospital-Derby Care Center

    Derby, Connecticut, 06418, United States

  • Smilow Cancer Hospital-Orange Care Center

    Orange, Connecticut, 06477, United States

  • Smilow Cancer Hospital-Waterbury Care Center

    Waterbury, Connecticut, 06708, United States

  • South Pointe Hospital

    Warrensville Heights, Ohio, 44122, United States

  • Southeast Cancer Center

    Cape Girardeau, Missouri, 63703, United States

  • Southeast Nebraska Cancer Center

    Lincoln, Nebraska, 68510, United States

  • Southeastern Medical Oncology Center-Clinton

    Clinton, North Carolina, 28328, United States

  • Southeastern Medical Oncology Center-Goldsboro

    Goldsboro, North Carolina, 27534, United States

  • Southeastern Medical Oncology Center-Jacksonville

    Jacksonville, North Carolina, 28546, United States

  • Southeastern Medical Oncology Center-Wilson

    Wilson, North Carolina, 27893, United States

  • Southern Illinois University School of Medicine

    Springfield, Illinois, 62702, United States

  • Southern Ohio Medical Center

    Portsmouth, Ohio, 45662, United States

  • Sparrow Hospital

    Lansing, Michigan, 48912, United States

  • Spector, David MD (UIA Investigator)

    Moline, Illinois, 61265, United States

  • Spectrum Health Reed City Hospital

    Reed City, Michigan, 49677, United States

  • Spectrum Health at Butterworth Campus

    Grand Rapids, Michigan, 49503, United States

  • Springfield Clinic

    Springfield, Illinois, 62702, United States

  • Springfield Regional Cancer Center

    Springfield, Ohio, 45504, United States

  • Springfield Regional Medical Center

    Springfield, Ohio, 45505, United States

  • Staten Island University Hospital

    Staten Island, New York, 10305, United States

  • Straub Clinic and Hospital

    Honolulu, Hawaii, 96813, United States

  • Strecker Cancer Center-Belpre

    Belpre, Ohio, 45714, United States

  • The Hospital of Central Connecticut

    New Britain, Connecticut, 06050, United States

  • The Mark H Zangmeister Center

    Columbus, Ohio, 43219, United States

  • The Toledo Hospital/Toledo Children's Hospital

    Toledo, Ohio, 43606, United States

  • The University of Kansas Cancer Center-Lee's Summit

    Lee's Summit, Missouri, 64064, United States

  • The University of Kansas Cancer Center-North

    Kansas City, Missouri, 64154, United States

  • The University of Kansas Cancer Center-South

    Kansas City, Missouri, 64131, United States

  • Toledo Clinic Cancer Centers-Bowling Green

    Bowling Green, Ohio, 43402, United States

  • Toledo Clinic Cancer Centers-Maumee

    Maumee, Ohio, 43537, United States

  • Toledo Clinic Cancer Centers-Monroe

    Monroe, Michigan, 48162, United States

  • Toledo Clinic Cancer Centers-Oregon

    Oregon, Ohio, 43616, United States

  • Toledo Clinic Cancer Centers-Toledo

    Toledo, Ohio, 43623, United States

  • Toledo Community Hospital Oncology Program CCOP

    Toledo, Ohio, 43617, United States

  • Toledo Radiation Oncology at Northwest Ohio Onocolgy Center

    Maumee, Ohio, 43537, United States

  • Trinity Medical Center

    Moline, Illinois, 61265, United States

  • Truman Medical Center

    Kansas City, Missouri, 64108, United States

  • Tulane University Health Sciences Center

    New Orleans, Louisiana, 70112, United States

  • UC Irvine Health/Chao Family Comprehensive Cancer Center

    Orange, California, 92868, United States

  • UH-Seidman Cancer Center at Saint John Medical Center

    Westlake, Ohio, 44145, United States

  • USC / Norris Comprehensive Cancer Center

    Los Angeles, California, 90033, United States

  • United Hospital

    Saint Paul, Minnesota, 55102, United States

  • Unity Hospital

    Fridley, Minnesota, 55432, United States

  • University Hospitals Parma Medical Center

    Parma, Ohio, 44129, United States

  • University Medical Center of Southern Nevada

    Las Vegas, Nevada, 89102, United States

  • University of Arkansas for Medical Sciences

    Little Rock, Arkansas, 72205, United States

  • University of Hawaii Cancer Center

    Honolulu, Hawaii, 96813, United States

  • University of Kansas Cancer Center

    Kansas City, Kansas, 66160, United States

  • University of Kansas Cancer Center-Overland Park

    Overland Park, Kansas, 66210, United States

  • University of Kansas Cancer Center-West

    Kansas City, Kansas, 66112, United States

  • University of Mississippi Medical Center

    Jackson, Mississippi, 39216, United States

  • University of Oklahoma Health Sciences Center

    Oklahoma City, Oklahoma, 73104, United States

  • University of Rochester

    Rochester, New York, 14642, United States

  • University of Toledo

    Toledo, Ohio, 43614, United States

  • University of Wisconsin Hospital and Clinics

    Madison, Wisconsin, 53792, United States

  • Upper Valley Medical Center

    Troy, Ohio, 45373, United States

  • Urology Cancer Center PC

    Omaha, Nebraska, 68130, United States

  • Valley Radiation Oncology

    Peru, Illinois, 61354, United States

  • Via Christi Hospital-Pittsburg

    Pittsburg, Kansas, 66762, United States

  • Vince Lombardi Cancer Clinic - Oshkosh

    Oshkosh, Wisconsin, 54904, United States

  • Vince Lombardi Cancer Clinic-Marinette

    Marinette, Wisconsin, 54143, United States

  • Vince Lombardi Cancer Clinic-Sheboygan

    Sheboygan, Wisconsin, 53081, United States

  • Vince Lombardi Cancer Clinic-Two Rivers

    Two Rivers, Wisconsin, 54241, United States

  • Walter Reed National Military Medical Center

    Bethesda, Maryland, 20889-5600, United States

  • Wayne Hospital

    Greenville, Ohio, 45331, United States

  • Wayne Memorial Hospital

    Goldsboro, North Carolina, 27534, United States

  • Wayne State University/Karmanos Cancer Institute

    Detroit, Michigan, 48201, United States

  • Weisberg Cancer Treatment Center

    Farmington Hills, Michigan, 48334, United States

  • Wesley Medical Center

    Wichita, Kansas, 67214, United States

  • West Jefferson Medical Center

    Marrero, Louisiana, 70072, United States

  • West Michigan Cancer Center

    Kalamazoo, Michigan, 49007, United States

  • Western Illinois Cancer Treatment Center

    Galesburg, Illinois, 61401, United States

  • Wilcox Memorial Hospital and Kauai Medical Clinic

    Lihue, Hawaii, 96766, United States

  • Yale University

    New Haven, Connecticut, 06520, United States

  • Yale-New Haven Hospital North Haven Medical Center

    North Haven, Connecticut, 06473, United States