Acupuncture before surgery may keep elderly minds clear
NCT ID NCT03606941
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether giving electroacupuncture 30 minutes before major surgery could lower the chance of postoperative delirium (sudden confusion) in patients aged 65 to 90. Over 1,100 participants were randomly assigned to receive real or sham acupuncture. The goal was to see if this simple, needle-based treatment could protect brain function after surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- electroacupuncture
- What this could lead to
- If it works, this could offer a simple, drug-free way to lower the risk of confusion after major surgery in older adults.
- What could go wrong
- The trial is completed but results are not yet widely confirmed. The effect may be small or not better than sham acupuncture.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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1,100 people
The number who actually took part.
- Started
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Sep 2018
- Finished
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Oct 2022
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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65 to 90 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Age≥65 and \<90 years old; 2. Planning to undergo select timed/limited surgery such as gastrointestinal tumor surgery, bile duct surgery and thoracic surgery etc under general anesthesia, and the estimated operation time is more than 2 hours;; 3. Treatment without radiotherapy or chemotherapy prior to surgery; 4. Agree to participate in this study and sign informed consent; Exclusion Criteria: 1. Refuse to participate in this study; 2. Preoperative history of schizophrenia, epilepsy, Parkinson's disease, or myasthenia gravis; 3. Inability to communicate in the preoperative period to complete preoperative evaluation because of severe dementia, coma, language barrier; 4. Brain injury or neurosurgery; 5. Critical condition (if the ASA grade is greater than or equal to grade IV before surgery); Severe renal impairment (dialysis treatment before surgery); Severe liver function impairment (Child-Pugh level C); Preoperative combined with severe heart disease, LVEF \< 30%; 6. Previous experience of acupoint stimulation therapy or non-insensitive to acupoint stimulation; 7. The attending physician or researcher considers that there are other circumstances (reasons to be noted) that are not suitable for participation in this study.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Electroacupuncture Apparatus
Tianjin, Tianjin Municipality, 300100, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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