Shock therapy? electrical acupoints may soothe chemo pain in kids with leukemia
NCT ID NCT07319481
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests if a gentle, non-invasive electrical stimulation on specific acupoints can reduce nerve pain caused by chemotherapy in children aged 10-17 with acute lymphoblastic leukemia. The treatment is given for 8 weeks, and researchers will check if it helps with pain, movement, mood, and quality of life. The goal is to see if this approach is practical and effective for easing these side effects.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Feb 2026
An estimate. Start dates often move.
- Expected to finish
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Jan 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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10 to 17 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * age between 10 and 17 years old * diagnosed with ALL * received neurotoxic chemotherapy * have developed score 9 or above CIPN symptoms according to Pediatric Chemotherapy-Induced Neuropathy (P-CIN) * able to communicate and read Chinese Exclusion Criteria: * receiving multiple cancer treatment * had a diagnosis of cancer in the central nervous system cancer, cancer relapse or secondary cancer * having other neuromuscular disorders, for example, traumatic brain injury and cerebral palsy * having other systematic diseases that cause toxicity in the peripheral nervous system, such as sickle cell disease (SCD), Guillain-Barre ́ Syndrome (GBS), anterior cutaneous nerve entrapment syndrome (ACNES), obstetric brachial plexus injury (OBPI), type I diabetes mellitus, postherpetic neuralgia (PHN), peroneal nerve injury, and reflex sympathetic dystrophy (RSD) * acupoints areas with injuries, wounds or allodynia * participated in any other CIPN non-pharmacological intervention programme * having any impaired bone marrow suppression * contraindications to TEAS : such as having a pacemaker, skin infection, damage, or allergy to the electrodes * suffering from mental illness or using antipsychotic drugs * parents and children refused to give consent.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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The Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital
Zhengzhou, China
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