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New hope for tough leukemia? early trial of eganelisib begins

NCT ID NCT06533761

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 28 times

Summary

This early-phase study tests a new drug called eganelisib, given alone or with standard chemotherapy (cytarabine), in about 125 adults whose acute myeloid leukemia (AML) or high-risk myelodysplastic syndrome (MDS) has returned or not responded to prior treatment. The main goals are to check the drug's safety, find the best dose, and see if it can shrink or control the cancer. This is not a cure study, as ongoing management is expected.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Anshutz Cancer Pavilion

    RECRUITING

    Aurora, Colorado, 80045, United States

    Contact Email: •••••@•••••

  • City of Hope

    RECRUITING

    Duarte, California, 91010, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cleveland Clinic

    RECRUITING

    Cleveland, Ohio, 44106, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Dana-Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital San Pedro de Alcántara

    RECRUITING

    Cáceres, 10003, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Universitari i Politècnic La Fe

    RECRUITING

    Valencia, 46026, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77054, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Memorial Sloan Kettering Cancer Center

    NOT_YET_RECRUITING

    New York, New York, 10065, United States

  • Memorial Sloan Kettering Cancer Center

    RECRUITING

    New York, New York, 10065, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Moffitt Cancer Center

    RECRUITING

    Tampa, Florida, 33612, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Montefiore Medical Center

    RECRUITING

    New York, New York, 10466, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ohio State University

    RECRUITING

    Columbus, Ohio, 43210, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Washington University in St Louis

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.