Scientists zap brain in 12 people to map electrical reactions
NCT ID NCT07179224
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study looked at how the brain's electrical activity changes when a magnetic stimulation device (rTMS) is applied to different spots on the forehead. Twelve adults each received one treatment session while their brain waves were recorded with EEG. The goal was simply to understand the brain's immediate response, not to treat any condition.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- transcranial magnetic stimulation (rTMS) device
- What this could lead to
- If successful, this could help refine how rTMS is delivered for conditions like depression or anxiety.
- What could go wrong
- This was a very small, early-stage study with only 12 participants. It measured brain activity, not treatment effects, so it may not lead to any direct clinical benefit.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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12 people
The number who actually took part.
- Started
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Sep 2025
- Finished
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Oct 2025
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age \> 19 years * Ability to determine the motor threshold of the participant. * Willingness to maintain on pre-study psychotherapeutic regime, and prescribed medications at a stable therapeutic dosage for at least 2 months prior to study entry. * Willingness to comply with study instructions and to return to the clinic for the required visits * Willingness to undergo EEG examination and proceed with the instructions from the study staff during the measurement * Women of child-bearing potential are required to use birth control measures during the whole duration of the study Exclusion Criteria: * electronic implants (Implanted stimulator devices in or near the head - rTMS devices are contraindicated for use in patients who have active or inactive implants including device leads, deep brain stimulators, cochlear implants, ocular implants, and vagus nerve stimulators, implanted devices such as cardiac pacemakers, defibrillators, and neurostimulators.), * metallic, ferromagnetic or other magnetic-sensitive implants/objects in or near the head\*, * application in the heart area, * persons with a tendency to seizure (hypotonic, epileptic), * ongoing anticoagulation therapy, * ongoing severe or life-threatening condition, * ongoing renal dialysis therapy or decompensated\*\* renal insufficiency, * decompensated\* hemorrhagic conditions, blood coagulation disorders, cardiovascular diseases, * malignant or benign tumour (within 30 cm of the treatment coil), * fever, * application over or in the near proximity (within 30 cm of the treatment coil) of tattoos with metallic ink * pregnancy or nursing * suicidal tendencies or recent attempt to commit suicide, * concurrent use of electroconvulsive therapy or vagus nerve stimulation, * ongoing or recent changes (less than 60 days) in intake doses of any pharmaceutical - products, standalone or in combination, that might lower the threshold of seizure potential, * ongoing withdrawal conditions from any dependence substance or medication associated with altered seizure risk history, * a psychotic disorder, including schizoaffective disorder, bipolar disease, or major depression with psychotic features, * history of primary or secondary tumors in CNS, cerebral aneurysm, * history of increased intracranial pressure or head trauma with loss of consciousness. * any medication that may alter EEG report (such as benzodiazepines, barbiturates, carbamazepine, valproate, phenothiazines, clozapine, tricyclic antidepressants, lithium, etc.), any other disease or condition at the investigator discretion that may pose risk to the patient or compromise the study * rTMS devices are contraindicated for use in patients who have conductive, ferromagnetic or other magnetic-sensitive metals implanted in their head (with some exceptions in the mouth - standard amalgam dental fillings, single post dental implants, and dental bridge work. When these objects are present monitor the patient during therapy and have the patient notify the operator of warming or other sensation; cease rTMS treatment in event of warming sensation) or within 30 cm of the treatment coil. (Examples include implanted electrodes/stimulators, aneurysm clips or coils, stents, bullet fragments, jewellery, and hair barrettes) \*\*This term applies to patients with a documented medical history of a decompensated health condition requiring medical treatment and/or medication, yet has not received such treatment and/or medication. Patients who use certain medications only for preventive purposes, without any proven previous health condition failure are not considered contraindicated.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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DP Neuro s.r.o.
Prague, Prague, 162 00, Czechia