ECT anesthetic doses under the microscope: no new treatment, just observation
NCT ID NCT07418463
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study watched 60 adults getting electroconvulsive therapy (ECT) for severe depression to see if their need for anesthesia changed over multiple sessions. Researchers measured the dose of anesthetic used each time and how it related to seizure quality and recovery. No new treatments were given—just routine care was observed.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
60 people
The number who actually took part.
- Started
-
Mar 2026
- Finished
-
Jun 2026
- Lead sponsor
-
A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult patients aged 18-65 years with an established indication for electroconvulsive therapy (ECT) who are scheduled to undergo multiple ECT sessions at a tertiary care hospital. Participants will be consecutively enrolled during the study period according to eligibility criteria. All procedures will be performed as part of routine clinical care.
- Ages
-
18 to 65 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18 to 65 years. * Scheduled to undergo electroconvulsive therapy (ECT) under elective conditions as part of routine clinical care. * ECT indication (e.g., major depressive disorder, bipolar depression, schizoaffective disorder, catatonia). * ASA Physical Status I-III. * Planned to receive multiple ECT sessions. * Able to provide written informed consent (participant and/or legally authorized representative). Exclusion Criteria: * Use of antiepileptic drugs or benzodiazepines that may affect seizure threshold. * ECT received within the past 6 months. * Severe cardiovascular, pulmonary, or neurologic comorbidity (investigator judgment). * Pregnancy or breastfeeding. * ASA Physical Status IV or higher. * Acute substance or alcohol use disorder/intoxication. * Conditions preventing EEG monitoring (e.g., scalp trauma, significant skin lesions, cranial implants). * Inability to obtain reliable BIS monitoring during anesthesia induction due to technical limitations.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Bipolar depression are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Izmir City Hospital
Izmir, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a Dopamine-Tuning drug lift bipolar depression?
- Scientists probe brain's reward system in mental illness
- Can talk therapy and social coaching ease early psychosis?
- Can a Low-Dose Add-On drug lift depression and boost thinking in bipolar disorder?
- Brain training may reshape brain chemistry in schizophrenia
- Could a single daily dose of clozapine work just as well?