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New hope for restless legs sufferers whose medication backfires

NCT ID NCT03218969

First seen Apr 27, 2026 · Last updated May 25, 2026 · Updated 5 times

Summary

This small study tested a drug called ecopipam in 10 adults with restless legs syndrome whose symptoms had gotten worse from their usual dopamine medication. The goal was to see if ecopipam could reduce symptom severity and the spread of symptoms to other body parts. Each person took ecopipam for 6 weeks and a placebo for 6 weeks, with a 2-week break in between, to compare the effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Houston Methodist Hospital

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.