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Eccentric cycling: a gentler path to heart attack recovery?

NCT ID NCT07729410

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time

Summary

This trial tests whether adding eccentric cycling—a type of exercise where muscles lengthen under tension—to standard cardiac rehabilitation can improve recovery in people who have had a heart attack. Eccentric exercise may allow higher muscle loads with less cardiovascular demand. Researchers will measure changes in blood proteins linked to exercise and physical function over a two-week program.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
eccentric cycling exercise added to standard cardiac rehabilitation
What this could lead to
If it works, this could point toward a more efficient rehab approach for heart attack recovery, potentially improving physical function with less strain on the heart.
What could go wrong
This is a small, early-stage trial with only 60 participants, so results may not apply broadly. The eccentric exercise is added to standard care, making it hard to isolate its specific benefit.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

Jul 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

50 to 75 years

Sex

Male participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria * Documented history of myocardial infarction confirmed by medical records. * Qualification for stage I comprehensive inpatient cardiac rehabilitation. * Clinically stable condition allowing participation in exercise-based cardiac rehabilitation. * New York Heart Association functional class I or II. * Moderate or good exercise tolerance, defined as an exercise capacity of at least 5 metabolic equivalents, assessed during an exercise test. * No cardiovascular contraindications to exercise testing or participation in exercise-based cardiac rehabilitation. * Ability to understand the study procedures and follow the instructions provided by the study personnel. * Provision of written informed consent to participate in the study. Exclusion Criteria: * Any contraindication to exercise-based cardiac rehabilitation or exercise testing. * Acute myocardial infarction within the first 4 days before planned initiation of exercise rehabilitation. * Unstable angina. * Significant left main coronary artery stenosis considered a contraindication to exercise by the treating cardiologist. * Symptomatic cardiac arrhythmias. * Symptomatic severe aortic stenosis. * Decompensated heart failure. * Acute pulmonary embolism or pulmonary infarction. * Deep vein thrombosis. * Recent or mobile intracardiac thrombus. * Acute myocarditis, endocarditis, or pericarditis. * Aortic dissection. * Symptomatic acquired second- or third-degree atrioventricular block without appropriate cardiac pacing. * Poorly controlled arterial hypertension. * Recent stroke or transient cerebral ischemic event. * Any acute or uncontrolled non-cardiovascular condition that may interfere with exercise testing or worsen during exercise, including febrile illness, clinically significant electrolyte abnormalities, uncontrolled hyperthyroidism, or clinically significant anemia. * Physical or cognitive impairment preventing safe completion of the study procedures, exercise testing, or training intervention. * Inability or unwillingness to provide written informed consent.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • Florian Ceynowa Specialist Hospital in Wejherowo

    Wejherowo, Pomeranian Voivodeship, 84-200, Poland

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