Eccentric cycling: a gentler path to heart attack recovery?
NCT ID NCT07729410
First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time
Summary
This trial tests whether adding eccentric cycling—a type of exercise where muscles lengthen under tension—to standard cardiac rehabilitation can improve recovery in people who have had a heart attack. Eccentric exercise may allow higher muscle loads with less cardiovascular demand. Researchers will measure changes in blood proteins linked to exercise and physical function over a two-week program.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- eccentric cycling exercise added to standard cardiac rehabilitation
- What this could lead to
- If it works, this could point toward a more efficient rehab approach for heart attack recovery, potentially improving physical function with less strain on the heart.
- What could go wrong
- This is a small, early-stage trial with only 60 participants, so results may not apply broadly. The eccentric exercise is added to standard care, making it hard to isolate its specific benefit.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jul 2026
An estimate. Start dates often move.
- Expected to finish
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Jul 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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50 to 75 years
- Sex
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Male participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria * Documented history of myocardial infarction confirmed by medical records. * Qualification for stage I comprehensive inpatient cardiac rehabilitation. * Clinically stable condition allowing participation in exercise-based cardiac rehabilitation. * New York Heart Association functional class I or II. * Moderate or good exercise tolerance, defined as an exercise capacity of at least 5 metabolic equivalents, assessed during an exercise test. * No cardiovascular contraindications to exercise testing or participation in exercise-based cardiac rehabilitation. * Ability to understand the study procedures and follow the instructions provided by the study personnel. * Provision of written informed consent to participate in the study. Exclusion Criteria: * Any contraindication to exercise-based cardiac rehabilitation or exercise testing. * Acute myocardial infarction within the first 4 days before planned initiation of exercise rehabilitation. * Unstable angina. * Significant left main coronary artery stenosis considered a contraindication to exercise by the treating cardiologist. * Symptomatic cardiac arrhythmias. * Symptomatic severe aortic stenosis. * Decompensated heart failure. * Acute pulmonary embolism or pulmonary infarction. * Deep vein thrombosis. * Recent or mobile intracardiac thrombus. * Acute myocarditis, endocarditis, or pericarditis. * Aortic dissection. * Symptomatic acquired second- or third-degree atrioventricular block without appropriate cardiac pacing. * Poorly controlled arterial hypertension. * Recent stroke or transient cerebral ischemic event. * Any acute or uncontrolled non-cardiovascular condition that may interfere with exercise testing or worsen during exercise, including febrile illness, clinically significant electrolyte abnormalities, uncontrolled hyperthyroidism, or clinically significant anemia. * Physical or cognitive impairment preventing safe completion of the study procedures, exercise testing, or training intervention. * Inability or unwillingness to provide written informed consent.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Florian Ceynowa Specialist Hospital in Wejherowo
Wejherowo, Pomeranian Voivodeship, 84-200, Poland
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