Backward-Pedaling bike may build strength with less oxygen
NCT ID NCT07815366
First seen Sep 11, 2026 · Last updated Sep 11, 2026
Summary
Researchers at the University of Zurich are testing whether eccentric cycling, a type of exercise where the rider resists backward-moving pedals on a motor-driven bike, can improve fitness and muscle strength over three months. The trial enrolls healthy adults without known heart or lung disease and compares eccentric cycling with standard cycling training. The goal is to see whether this low-oxygen, high-force exercise approach works in a real-world rehabilitation setting.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- eccentric cycling exercise on a motor-driven ergometer
- What this could lead to
- If it works, eccentric cycling could offer a low-strain way for people with heart or lung conditions to build fitness and strength during rehabilitation.
- What could go wrong
- The trial is small and enrolls healthy volunteers, not patients, so results may not apply to people with cardiopulmonary disease. Eccentric exercise can cause muscle soreness, and the approach requires specialized equipment.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 12 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2026
- Expected to finish
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Jul 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Healthy participants without known Cardiopulmonary disease. * Provided written informed consent * Wiling to voluntarily exercise for 3 month on the eccentric ergometer without a specific indication for rehabilitation Exclusion Criteria: * Inability to follow the exercise procedure. * Vulnerable participants (e.g. minors, participants incapable of judgment or participants under tutelage) will not be included into the study.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Universitätsspital Zürich
Zurich, Canton of Zurich, 8091, Switzerland