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Timing of facial fracture surgery: does faster mean better?

NCT ID NCT07749729

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time

Summary

This study compares two approaches to surgery for facial fractures: operating within 72 hours of injury versus waiting longer. It will track how well patients heal, including bone healing, function, and appearance. The goal is to see if earlier surgery leads to better outcomes for people with these injuries.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Timing of open reduction and internal fixation (ORIF) surgery
What this could lead to
If early surgery proves better, it could guide surgeons to operate sooner on facial fractures, potentially improving recovery and cosmetic results.
What could go wrong
This is a small study, and results may not apply to all patients. Surgery timing is just one factor; individual injuries and health can influence outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

50 people

The number who actually took part.

Started

Feb 2025

Finished

Mar 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

patients with maxillofacial fractures requiring open reduction and internal fixation (ORIF) who present to the participating governmental hospitals in Sana'a, Yemen. Participants will be enrolled prospectively and classified into early (≤72 hours) or delayed (\>72 hours) intervention groups according to the timing of surgical treatment.

Ages

12 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Aged 12 years and older. * Patients diagnosed with maxillofacial fractures requiring open reduction and internal fixation (ORIF). * Patients presenting with maxillofacial trauma treated within the participating study centers. * Patients assigned to either the early intervention group (≤72 hours after injury) or the delayed intervention group (\>72 hours after injury). * Patients able to provide written informed consent or whose legally authorized representative provides consent when applicable. * Patients willing to comply with the scheduled follow-up visits. years and older. Exclusion Criteria: * Patients managed with conservative (non-surgical) treatment. * Patients with previous maxillofacial fractures affecting the study site. * Patients with incomplete baseline clinical data. * Patients with severe medical conditions precluding surgical treatment or follow-up. * Patients lost to follow-up before completion of the primary outcome assessment. * Patients who decline to participate or withdraw informed consent.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Al-Gomhori Teaching Hospital

    Sanaa, Amanat Al Asimah, Yemen

  • Military Hospital

    Sanaa, Amanat Al Asimah, Yemen

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